P9547
Prilocaine hydrochloride
≥98% (TLC)
Synonym(s):
N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C13H20N2O · HCl
CAS Number:
Molecular Weight:
256.77
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
217-244-0
MDL number:
InChI key
BJPJNTKRKALCPP-UHFFFAOYSA-N
InChI
1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
SMILES string
Cl[H].CCCNC(C)C(=O)Nc1ccccc1C
assay
≥98% (TLC)
form
powder
originator
AstraZeneca
Quality Level
Gene Information
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Related Categories
Biochem/physiol Actions
Used for local nerve block and for spinal anesthesia; pharmacological properties are similar to those of lidocaine.
Features and Benefits
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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V Gebhardt et al.
Acta anaesthesiologica Scandinavica, 57(2), 249-256 (2012-12-04)
Hyperbaric prilocaine 20 mg/ml may be preferable for perianal outpatient surgery. The aim of this prospective, single-centre, randomised, single-blinded, controlled clinical trial was to determine the optimal dosage of hyperbaric prilocaine 20 mg/ml for a spinal anaesthesia (SPA) in patients
S Schreiber et al.
European journal of pediatrics, 172(2), 265-268 (2012-10-25)
Venipuncture and intravenous cannulation are the most common painful procedures performed on children. The most widely used topical anesthetic is eutectic mixture of local anesthetics (EMLA). EMLA use is associated with a transient cutaneous vasoconstriction which can make it difficult
Young-Eun Moon et al.
Archives of physical medicine and rehabilitation, 94(5), 919-924 (2012-12-25)
To compare the effects of a vapocoolant spray and an eutectic mixture of local anesthetics (EMLA) cream in reducing pain during needle electromyography examination. Randomized controlled trial. Physical medicine and rehabilitation department of a university hospital. Adults who underwent needle
Michelle Briggs et al.
The Cochrane database of systematic reviews, 11, CD001177-CD001177 (2012-11-16)
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings. Topical treatments to reduce pain during and between dressing changes are sometimes used.
Nezih Sertoz et al.
Foot & ankle international, 34(1), 85-90 (2013-02-07)
The objective of the present study was to explore the effects of deficiencies in glucose regulation on the onset, regression, and block performance times in a group of patients with diabetes-related foot problems. Forty-eight patients with American Society of Anesthetists
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