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G7132

Sigma-Aldrich

Sodium glycocholate hydrate

≥95% (TLC)

Synonym(s):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide sodium salt, Glycocholic acid sodium salt hydrate, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)glycine sodium salt, N-Cholylglycine sodium salt

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100 MG
CN¥748.53
500 MG
CN¥1,249.45
1 G
CN¥1,545.16
5 G
CN¥5,811.17
25 G
CN¥22,416.36
50 G
CN¥30,101.96

CN¥748.53

Available to ship onApril 14, 2025Details

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100 MG
CN¥748.53
500 MG
CN¥1,249.45
1 G
CN¥1,545.16
5 G
CN¥5,811.17
25 G
CN¥22,416.36
50 G
CN¥30,101.96

About This Item

Linear Formula:
C26H42NO6Na · xH2O
CAS Number:
338950-81-5
Molecular Weight:
487.60 (anhydrous basis)
Beilstein:
3854517
EC Number:
212-730-9
MDL number:
MFCD09037360
UNSPSC Code:
12161900
PubChem Substance ID:
24895292
NACRES:
NA.25

CN¥748.53

Available to ship onApril 14, 2025Details

Request a Bulk Order

description

anionic

Quality Level

200

Assay

≥95% (TLC)

mol wt

micellar avg mol wt 900(lit.)

aggregation number

1.9

CMC

13 mM (20-25°C)(lit.)

mp

210-215 °C (subl.) (lit.)

SMILES string

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCC([O-])=O

InChI

1S/C26H43NO6.Na.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);;1H2/q;+1;/p-1/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;;/m1../s1

InChI key

YWROUPFMHKARON-HJRQWJHVSA-M

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Show Differences

1 of 4

This Item
T0557C644530968
Sodium glycocholate hydrate ≥95% (TLC)

G7132

Sodium glycocholate hydrate

Sodium taurodeoxycholate hydrate BioXtra, ≥97% (TLC)

T0557

Sodium taurodeoxycholate hydrate

Sodium cholate hydrate BioXtra, ≥99%

C6445

Sodium cholate hydrate

Sodium deoxycholate monohydrate BioUltra, ≥99.0% (NT)

30968

Sodium deoxycholate monohydrate

aggregation number

1.9

aggregation number

6

aggregation number

2-3

aggregation number

3-12

description

anionic

description

anionic

description

anionic

description

anionic

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

mp

210-215 °C (subl.) (lit.)

mp

-

mp

-

mp

-

mol wt

micellar avg mol wt 900(lit.)

mol wt

micellar avg mol wt 3100

mol wt

micellar avg mol wt 900-1300

mol wt

average mol wt 1200-5000

General description

Sodium glycocholate hydrate is a conjugated bile salt and an ionic biologic detergent. [1]

Application

Sodium glycocholate hydrate has been used in a study to assess serum total bile acids via a fluorimetric and enzymatic method. [2] It has also been used in a study to investigate its effect on micelle formation and solubilization of testosterone. [3]

Biochem/physiol Actions

Bile Salt

Preparation Note

This product is synthetically prepared from naturally occuring cholic acid (Product No. C1129).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000435661
    0000435661
    0000436676
    0000436676
    0000433877

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    Micelle formation and testosterone solubilization by sodium glycocholate.
    L Martis et al.
    Journal of pharmaceutical sciences, 61(11), 1757-1761 (1972-11-01)
    Feilong Sun et al.
    Colloids and surfaces. B, Biointerfaces, 170, 521-528 (2018-07-04)
    Poorly soluble vitamin K cannot be absorbed by patients suffering from cholestasis due to extremely low level of bile salts in the intestine. A formulation of vitamin K including glycocholic acid (i.e. Konakion® MM), does not increase bioavailability because it
    Mari Araki et al.
    Journal of biochemistry, 160(5), 269-279 (2016-11-02)
    DDHD2 has been reported to exhibit phospholipase A
    Monalisa Mohapatra et al.
    Langmuir : the ACS journal of surfaces and colloids, 27(22), 13461-13467 (2011-10-07)
    The interaction of submicellar concentrations of various physiologically important unconjugated [sodium deoxycholate (NaDC), sodium cholate (NaC)] and conjugated [sodium glycodeoxycholate (NaGDC), sodium glycocholate (NaGC), sodium taurodeoxycholate (NaTDC), sodium taurocholate (NaTC)] bile salts with dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) small unilamellar
    Robert Creutznacher et al.
    Chembiochem : a European journal of chemical biology, 21(7), 1007-1021 (2019-10-24)
    Bile acids have been reported as important cofactors promoting human and murine norovirus (NoV) infections in cell culture. The underlying mechanisms are not resolved. Through the use of chemical shift perturbation (CSP) NMR experiments, we identified a low-affinity bile acid
    View All Related Papers

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