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Key Documents

G2878

Sigma-Aldrich

Glycocholic acid hydrate

synthetic, ≥97% (HPLC)

Synonym(s):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Cholylglycine, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)-glycine

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¥7,830.80

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Estimated to ship on2025年7月23日Details


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1 EA
¥7,830.80

About This Item

Empirical Formula (Hill Notation):
C26H43NO6 · xH2O
CAS Number:
Molecular Weight:
465.62 (anhydrous basis)
Beilstein:
2955826
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

¥7,830.80


Estimated to ship on2025年7月23日Details


Request a Bulk Order

biological source

synthetic

Quality Level

description

anionic

Assay

≥97% (HPLC)

form

powder

mol wt

average mol wt 1000

aggregation number

2.1

technique(s)

enzyme immunoassay: suitable

CMC

7.1

functional group

amide

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1 of 4

This Item
70533085580705322
mass shift

M+8

mass shift

M+8

mass shift

-

mass shift

M+3

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

-

technique(s)

mass spectrometry (MS): suitable

isotopic purity

98 atom % D

isotopic purity

97 atom % D

isotopic purity

-

isotopic purity

98 atom % D

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

Application

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. [1] It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system. [2]

Biochem/physiol Actions

Bile Acid

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yazhou He et al.
PloS one, 9(3), e91202-e91202 (2014-03-14)
Association between the single nucleotide polymorphism rs3218536 (known as Arg188His) located in the X-ray repair cross complementing group 2 (XRCC2) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to
Konstantin Kazankov et al.
Hepatology (Baltimore, Md.), 60(2), 521-530 (2014-03-14)
Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C
Examination of the Interaction of Chitosan and Oil-in-Water Emulsions Under Conditions Simulating the Digestive System Using Confocal Microscopy
Helgason, T., et al.
Journal of Aquatic Food Product Technology, 17, 216-233 (2008)
Raj S Bhopal et al.
The lancet. Diabetes & endocrinology, 2(3), 218-227 (2014-03-14)
The susceptibility to type 2 diabetes of people of south Asian descent is established, but there is little trial-based evidence for interventions to tackle this problem. We assessed a weight control and physical activity intervention in south Asian individuals in
Matthias Laska
Chemical senses, 39(5), 415-424 (2014-03-14)
Using a conditioning paradigm, the olfactory sensitivity of CD-1 mice for a homologous series of aliphatic 2-ketones (2-butanone to 2-nonanone) and several of their isomeric forms was investigated. With all 11 odorants, the animals significantly discriminated concentrations as low as

Protocols

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

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Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

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