Key Documents

View All Documentation

G019

Muscimol hydrobromide

Name: Muscimol hydrobromide
Brand: SIGMA

≥98% (HPLC), GABAA receptor agonist, solid

Synonym(s):

5-Aminomethyl-3-hydroxyisoxazole hydrobromide

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₄H₆N₂O₂ · HBr

CAS Number:

18174-72-6

Molecular Weight:

195.01

UNSPSC Code:

12352200

PubChem Substance ID:

24278168

NACRES:

NA.77

MDL number:

MFCD00055184

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Muscimol hydrobromide, ≥98% (HPLC), solid

Quality Level

100

assay

≥98% (HPLC)

form

solid

color

off-white to tan

solubility

H₂O: >10 mg/mL

storage temp.

2-8°C

SMILES string

Br[H].NCc1cc(O)no1

InChI

1S/C4H6N2O2.BrH/c5-2-3-1-4(7)6-8-3;/h1H,2,5H2,(H,6,7);1H

InChI key

OPZOJWHOZRKYQX-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Description

Biochem/physiol Actions

Muscimol hydrobromide is a GABA_A receptor agonist.

Features and Benefits

This compound is featured on the GABAA Receptors and GABAC Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

DISCOVER Bioactive Small Molecules for Neuroscience

Cortical State Fluctuations during Sensory Decision Making.

Elina A K Jacobs et al.

Current biology : CB, 30(24), 4944-4955 (2020-10-24)

In many behavioral tasks, cortex enters a desynchronized state where low-frequency fluctuations in population activity are suppressed. The precise behavioral correlates of desynchronization and its global organization are unclear. One hypothesis holds that desynchronization enhances stimulus coding in the relevant

Medial Septum Modulates Cellular Response Induced in Hippocampus on Microinjection of Cholinergic Agonists into Hypothalamic Lateral Supramammillary Nucleus.

Mohammed Z Ariffin et al.

Frontiers in neuroanatomy, 11, 79-79 (2017-10-03)

Cholinergic mechanisms in supramammillary nucleus (SuM), especially the lateral SuM (lSuM) modulates septo-hippocampal neural activity. The lSuM, as compared to the contiguous medial SuM (mSuM) has relatively dense projections to hippocampus and cingulate cortex (Cg). In the present study, we

Behaviorally Selective Engagement of Short-Latency Effector Pathways by Motor Cortex.

Andrew Miri et al.

Neuron, 95(3), 683-696 (2017-07-25)

Blocking motor cortical output with lesions or pharmacological inactivation has identified movements that require motor cortex. Yet, when and how motor cortex influences muscle activity during movement execution remains unresolved. We addressed this ambiguity using measurement and perturbation of motor

View All Related Papers

Global Trade Item Number

SKU	GTIN
G019-5MG	04061833623367
G019-100MG	04061832082127
G019-10MG	04061832082134
G019-25MG	04061833623350