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Q5001

Supelco

Quinidine gluconate salt

analytical standard

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Empirical Formula (Hill Notation):
C20H24N2O2 · C6H12O7
CAS Number:
7054-25-3
Molecular Weight:
520.57
EC Number:
230-333-9
MDL number:
MFCD00067566
UNSPSC Code:
41116107
PubChem Substance ID:
329823867
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

application(s)

food and beverages

format

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K D Miller et al.
The New England journal of medicine, 321(2), 65-70 (1989-07-13)
During the past decade the incidence of Plasmodium falciparum malaria in the United States has increased 10-fold. Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for
Proarrhythmia: disparity of programmed electrical stimulation results and spontaneous occurrence: a case report.
A E Alicea et al.
Maryland medical journal (Baltimore, Md. : 1985), 40(6), 521-523 (1991-06-01)
D J Weiss et al.
Journal of the American Veterinary Medical Association, 196(3), 472-475 (1990-02-01)
Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs
A Garg et al.
Journal of cardiovascular electrophysiology, 9(6), 642-647 (1998-07-08)
A case is presented of an 18-year-old male who had been resuscitated following an episode of sudden death due to ventricular fibrillation. The patient was noted to have an abnormal deflection in the terminal QRS on surface ECG and an
D Darbar et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 53(6), 655-658 (1996-03-15)
The effect of a polyvinyl chloride (PVC) i.v. administration system on the availability of quinidine gluconate was studied. Quinidine gluconate diluted in 5% dextrose injection was administered intravenously to five healthy volunteers via conventional PVC infusion sets, and the subjects
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