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Q5001

Supelco

Quinidine gluconate salt

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H24N2O2 · C6H12O7
CAS Number:
Molecular Weight:
520.57
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

application(s)

food and beverages

format

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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    Malaria and hereditary elliptocytosis.
    Fouad N Boctor et al.
    American journal of hematology, 83(9), 753-753 (2007-08-19)
    V F Mauro et al.
    DICP : the annals of pharmacotherapy, 24(3), 252-254 (1990-03-01)
    The effect of aluminum hydroxide gel on quinidine gluconate bioavailability was studied in eight nonsmoking healthy male volunteers. Subjects were randomized to receive quinidine gluconate 648 mg with and without 30 mL of aluminum hydroxide gel. The mean area under
    B H Ackerman et al.
    DICP : the annals of pharmacotherapy, 23(5), 375-378 (1989-05-01)
    The formation rate constant and elimination rate constant for 3-hydroxyquinidine were determined in eight patients with ventricular tachycardia. These two parameters (mean +/- SD) were found to be 0.784 +/- 0.202 and 0.042 +/- 0.058 h-1, respectively. Coefficients of determination
    D J Weiss et al.
    Journal of the American Veterinary Medical Association, 196(3), 472-475 (1990-02-01)
    Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs
    A Garg et al.
    Journal of cardiovascular electrophysiology, 9(6), 642-647 (1998-07-08)
    A case is presented of an 18-year-old male who had been resuscitated following an episode of sudden death due to ventricular fibrillation. The patient was noted to have an abnormal deflection in the terminal QRS on surface ECG and an

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