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PHR1881

Supelco

Articaine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Articaine hydrochloride, 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester hydrochloride, Carticaine chlorhydrate, Carticaine hydrochloride
Empirical Formula (Hill Notation):
C13H20N2O3S · HCl
CAS Number:
23964-57-0
Molecular Weight:
320.84
EC Number:
245-957-7
MDL number:
MFCD00190157
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. Y0000079
traceable to USP 1042918

API family

articaine

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

CC1=CSC(C(OC)=O)=C1NC(C(C)NCCC)=O.Cl

InChI

1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H

InChI key

GDWDBGSWGNEMGJ-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Articaine is an amide local anesthetic widely used in dentistry. Articaine acts by inhibition of nerve impulse conduction by blockade of sodium channels.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB0608 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Product No.
Description
Pricing

Y0000079

Articaine hydrochloride, European Pharmacopoeia (EP) Reference Standard

Y0000081

Articaine impurity E, European Pharmacopoeia (EP) Reference Standard

1042918

Articaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1042907

Articaine, United States Pharmacopeia (USP) Reference Standard

1042929

Articaine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1042930

Articaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1042962

Articaine Related Compound E, United States Pharmacopeia (USP) Reference Standard

PHR1882

Articaine, Pharmaceutical Secondary Standard; Certified Reference Material

07356

4-Methyl-N-propyl-3-[[(2RS)-2-(propylamino)propanoyl]amino]thiophene-2-carboxamide hydrochloride, reference material

07380

1-Methylethyl 4-methyl-3-[[(2RS)-2-(propylamino)-propanoyl]amino]thiophene-2-carboxylate hydrochloride, reference material

CRM69760

Methyl 3-[[(2RS)-2-bromopropanoyl]amino]-4-methylthiophene-2-carboxylate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

CRM72531

Methyl 3-[[(2RS)-2-(ethylamino)propanoyl]amino]-4-methylthiophene-2- carboxylate hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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