Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN
All Photos(1)

Key Documents

View All Documentation

PHR1252

Supelco

Procainamide hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide

Sign Into View Organizational & Contract Pricing

Select a Size

500 MG
CN¥1,464.20

CN¥1,464.20

Available to ship onApril 23, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
500 MG
CN¥1,464.20

About This Item

Linear Formula:
H2NC6H4CONHCH2CH2N(C2H5)2·HCl
CAS Number:
614-39-1
Molecular Weight:
271.79
Beilstein:
3729517
EC Number:
210-381-7
MDL number:
MFCD00012998
UNSPSC Code:
41116107
PubChem Substance ID:
329823255
NACRES:
NA.24

CN¥1,464.20

Available to ship onApril 23, 2025Details

Request a Bulk Order

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. P3050000
traceable to USP 1563502

API family

procainamide

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

167-169 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SML2088P9391PHR1713
Procainamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

PHR1252

Procainamide hydrochloride

Procainamide hydrochloride ≥98% (HPLC)

SML2088

Procainamide hydrochloride

Procainamide hydrochloride

P9391

Procainamide hydrochloride

Proguanil hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

PHR1713

Proguanil hydrochloride

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

-

format

neat

Quality Level

300

Quality Level

-

Quality Level

-

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-30°C

General description

Procainamide hydrochloride belongs to the class I of antiarrhythmic drugs and is used for the management of heart arrhythmia in cardiac patients. It is also proposed to exhibit chemoprotective behavior against cisplatin-induced kidney toxicity.[1][2][3]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Procainamide hydrochloride may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical preparations by spectrophotometric[3] and electrophoretic techniques.[4]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4012 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Spectrophotometric determination of procainamide hydrochloride using sodium periodate
    Al-Tamrah S and Al-Abbad,S
    Arabian Journal of Chemistry, 8(5), 609-613 (2015)
    Reduction of cisplatin hepatotoxicity by procainamide hydrochloride in rats
    Zicca A, et al.
    European Journal of Pharmacology, 442(3), 265-272 (2002)
    Spectrophotometric determination of nicoumalone, acebutolol hydrochloride and procainamide hydrochloride
    Sastry CSP, et al.
    Talanta, 38(9), 1057-1060 (1991)
    Z Wojnarowska et al.
    The Journal of chemical physics, 136(16), 164507-164507 (2012-05-09)
    The pharmaceuticals, procaine hydrochloride and procainamide hydrochloride, are glass-forming as well as ionically conducting materials. We have made dielectric measurements at ambient and elevated pressures to characterize the dynamics of the ion conductivity relaxation in these pharmaceuticals, and calorimetric measurements
    Ian G Stiell et al.
    Annals of emergency medicine, 57(1), 13-21 (2010-09-25)
    Although recent-onset atrial fibrillation and flutter are common arrhythmias managed in the emergency department (ED), there is insufficient evidence to help physicians choose between 2 competing treatment strategies, rate control and rhythm control. We seek to evaluate variation in ED
    View All Related Papers

    Articles

    Released N-Glycan Analysis of a Therapeutic Antibody Using BIOshell™ Glycan Column

    This application note describes the released N-Glycan analysis of a monoclonal antibody, cetuximab, labeled with procainamide, using a BIOshell™ Glycan HPLC column.

    Quality Attribute Determination of Monoclonal Antibodies

    Workflows for monoclonal antibody adalimumab characterization ensure drug safety and efficacy through critical quality attribute analysis.

    Protocols

    Released N-Linked Glycan Analysis Workflow of Adalimumab

    A step-by-step protocol for released N-linked glycan analysis of the monoclonal antibody adalimumab, based on UHPLC-FLR-MS and procainamide labeling.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service