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Merck
CN

P3347

Prilocaine hydrochloride

meets USP testing specifications

Synonym(s):

N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H20N2O · HCl
CAS Number:
1786-81-8
Molecular Weight:
256.77
NACRES:
NA.21
PubChem Substance ID:
24898404
UNSPSC Code:
12352200
EC Number:
217-244-0
MDL number:
MFCD00079279

Key Documents

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InChI key

BJPJNTKRKALCPP-UHFFFAOYSA-N

InChI

1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H

SMILES string

Cl[H].CCCNC(C)C(=O)Nc1ccccc1C

agency

USP/NF, meets USP testing specifications

form

solid

application(s)

pharmaceutical (small molecule)

Quality Level

200

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Storage Class

11 - Combustible Solids

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Certificates of Analysis (COA)

Lot/Batch Number
1417729V
087H1027
1417729
086K1927
076K1046

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Brett J Wong
American journal of physiology. Regulatory, integrative and comparative physiology, 304(8), R651-R656 (2013-02-15)
We tested the hypothesis that inhibition of cutaneous sensory nerves would attenuate reflex cutaneous vasodilation in response to an increase in core temperature. Nine subjects were equipped with four microdialysis fibers on the forearm. Two sites were treated with topical
Rebeca M Plank et al.
Journal of pediatric urology, 9(1), e86-e90 (2012-10-30)
We report two cases of newborns who developed marked local edema after application of a eutectic mixture of local anesthetic (EMLA) topical anesthetic cream for neonatal male circumcision (NMC). Although local edema and erythema are known potential side effects of
Devendra Gupta et al.
Anesthesia and analgesia, 116(3), 568-571 (2013-02-13)
Topical capsaicin and eutectic mixture of local anesthetics (EMLA) have been found to be equally effective in minimizing the pain of venipuncture. After the injection of capsaicin, both tertiary amine local anesthetics and their quaternary ammonium derivatives can elicit a
Marco Bragagni et al.
International journal of pharmaceutics, 441(1-2), 468-475 (2012-11-21)
The use of injectable local anaesthetics for the treatment of severe postoperative pain is limited by the short duration of the painkilling effect. Pre-formulation studies were carried out for the development of an injectable microparticle formulation for controlled release of
Stephanie C J Keating et al.
PloS one, 7(9), e44437-e44437 (2012-09-13)
Ear tattooing is a routine procedure performed on laboratory, commercial and companion rabbits for the purpose of identification. Although this procedure is potentially painful, it is usually performed without the provision of analgesia, so compromising animal welfare. Furthermore, current means
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