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P2939060

Prilocaine hydrochloride

Name: Prilocaine hydrochloride
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₂₀N₂O · HCl

CAS Number:

1786-81-8

Molecular Weight:

256.77

MDL number:

MFCD00079279

UNSPSC Code:

41116107

PubChem Substance ID:

329820155

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

prilocaine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CCCNC(C)C(=O)Nc1ccccc1C

InChI

1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H

InChI key

BJPJNTKRKALCPP-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Related Categories

Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Prilocaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Lot/Batch Number

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An uncommon side effect in a common procedure: a case report of an adverse reaction to prilocaine during a Bier's block.

Gareth Rooke et al.

The New Zealand medical journal, 127(1407), 75-79 (2014-12-23)

This case report describes a rare side effect during a Bier's block. During local anaesthetic injection, the patient suffered a sudden onset painful petechial rash localised to the upper limb, distal to the tourniquet, without systemic effect. After deflation of

Improving the local anesthesia experience for our patients.

Gregori M Kurtzman

Dentistry today, 33(4), 120-120 (2014-05-06)

Methemoglobinemia induced by lidocaine-prilocaine cream.

Oded Shamriz et al.

The Israel Medical Association journal : IMAJ, 16(4), 250-254 (2014-05-20)

With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues may be oxygen-resistant cyanosis and

Comparison of clinical effects of prilocaine, dexamethasone added to prilocaine and levobupivacaine on brachial plexus block.

Aykut Saritas et al.

JPMA. The Journal of the Pakistan Medical Association, 64(4), 433-436 (2014-05-29)

To determine whether the addition of 8 mg dexamethasone to axillary brachial plexus block would prolong the duration of sensory and motor block in patients undergoing hand and forearm surgery. The prospective, randomised, double-blinded study was conducted at the Eskisehir

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.

Susan Parekh et al.

The Cochrane database of systematic reviews, 12(12), CD009742-CD009742 (2014-12-24)

Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiological response to procedures. Studies of effectiveness of

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