Skip to Content

很抱歉，目前系统维护中。在此期间，网站下单功能无法使用。给您带来不便，深表歉意。如需其他帮助，请联系客户联络中心：400 620 3333。

Merck
CN
All Photos(4)

Key Documents

View All Documentation

EDS

Sigma-Aldrich

Ethylenediaminetetraacetic acid

BioUltra, anhydrous, ≥99% (titration)

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

Sign Into View Organizational & Contract Pricing

Select a Size

25 G
CN¥807.54
100 G
CN¥2,028.06
500 G
CN¥6,183.47
1 KG
CN¥11,052.04
25 KG
inquire
25 KG
CN¥81,199.39

CN¥807.54

Available to ship onApril 07, 2025Details

Request a Bulk Order
All Photos(4)

Select a Size

Change View
25 G
CN¥807.54
100 G
CN¥2,028.06
500 G
CN¥6,183.47
1 KG
CN¥11,052.04
25 KG
inquire
25 KG
CN¥81,199.39

About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
60-00-4
Molecular Weight:
292.24
Beilstein:
1716295
EC Number:
200-449-4
MDL number:
MFCD00003541
UNSPSC Code:
12352116
eCl@ss:
39030907
PubChem Substance ID:
24894713
NACRES:
NA.77

CN¥807.54

Available to ship onApril 07, 2025Details

Request a Bulk Order

grade

anhydrous

Quality Level

200

product line

BioUltra

Assay

≥99% (titration)

form

powder

reaction suitability

reagent type: chelator

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

solubility

water: soluble 0.4 g/L at 20 °C

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
H3375H7523H6147
HEPES BioPerformance Certified, ≥99.5% (titration), suitable for cell culture

H4034

HEPES

HEPES ≥99.5% (titration)

H3375

HEPES

HEPES BioXtra, pH 5.0-6.5 (1 M in H2O), ≥99.5% (titration)

H7523

HEPES

HEPES BioXtra, suitable for mouse embryo cell culture, ≥99.5% (titration)

H6147

HEPES

technique(s)

cell culture | mammalian: suitable, competitive inhibition ELISA: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | embryo: suitable

grade

BioPerformance Certified

grade

-

grade

-

grade

-

Quality Level

400

Quality Level

400

Quality Level

400

Quality Level

400

application(s)

clinical research
diagnostic assay manufacturing
general analytical
life science and biopharma

application(s)

diagnostic assay manufacturing
general analytical
life science and biopharma
pharmaceutical

application(s)

diagnostic assay manufacturing

application(s)

-

form

crystalline powder

form

crystalline powder

form

powder

form

powder

General description

Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a versatile compound in household with industrial applications. EDTA chelates metal divalent cations like calcium, magnesium, zinc, copper, manganese by forming metal-EDTA complexes. It finds its application in cleaning products and detergent formulations. In paper and pulp industries, EDTA reduces the adverse effect of metal ions on bleaching. It functions as an antibacterial agent by removing calcium and magnesium divalent cations from the outer membrane and causes loss of lipopolysaccharide from the membrane, making the bacteria susceptible to bactericidal agents. Free EDTA has adverse effect on reproduction and development in mammals.[1] EDTA can chelate ions from deposits that contribute to atherosclerosis, cancers and heart diseases. It can help to overcome cell membrane injury by reducing radical reactions and oxidation processes. It binds to calcium and reduces the risk of hypercalcinemia in cancer patients. Transmembrane ammonium EDTA gradient method aids in drug delivery, increasing drug retention and efficacy of therapeutics and lowers the cytotoxicity levels.[2]

Application

EDTA has been used:
  • as a medium supplement in embryo culture using synthetic oviduct fluid culture 1 (SOFC1) medium[3]
  • in incubation of EpCAM+ cells with fluorescein isothiocyanate (FITC) conjugated antibody for cell sorting analysis[4]
  • in pre-treatment of single cell suspension of dendritic cells from spleen for cell sorting with magnetic beads[5]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0000358170
    0000358089
    0000321957
    0000321956
    BCCH2205

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    Menges M, et al.
    The Journal of Experimental Medicine, 195(1), 15-22 (2002)
    Effect of the absence or presence of various protein supplements on further development of bovine oocytes during in vitro maturation
    Ali A and Sirard M
    Biology of Reproduction, 66(4), 901-905 (2002)
    The application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH4EDTA gradient
    Song Y, et al.
    International journal of nanomedicine, 9, 3611-3621 (2014)
    The phenotypes of pluripotent human hepatic progenitors
    Schmelzer E, et al.
    Stem Cells, 24(8), 1852-1858 (2006)
    EDTA: the chelating agent under environmental scrutiny
    Oviedo C and Rodriguez J
    Quimica nova, 26(6), 901-905 (2003)
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service