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About This Item
Empirical Formula (Hill Notation):
C21H29N3O
CAS Number:
Molecular Weight:
339.47
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
SMILES string
CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C
InChI key
UVTNFZQICZKOEM-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
disopyramide
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Disopyramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Class IA antiarrhythmic; sodium channel blocker
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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S Y Kim et al.
Drug safety, 5(6), 393-420 (1990-11-01)
Quinidine, procainamide and disopyramide are antiarrhythmic drugs in the class 1A category. These drugs have a low toxic to therapeutic ratio, and their use is associated with a number of serious adverse effects during long term therapy and life-threatening sequelae
L Sathyavagiswaran
Journal of forensic sciences, 32(6), 1813-1818 (1987-11-01)
Disopyramide is an oral antiarrhythmic drug which reduces conduction velocity, prolongs duration of action potential and the effective refractory period, and exerts vagolytic properties. The drug is usually well absorbed orally. The principal use of the drug is to suppress
C Barnay
Annales de cardiologie et d'angeiologie, 41(8), 449-453 (1992-10-01)
Disopyramide is a Vaughan-Williams class Ia antiarrhythmic, which is distinguished by its anticholinergic activity, which is due to its active metabolite: mono-N-alkyl disopyramide. In cells with a rapid response, such as those in the His-Purkinje tissue, it depresses conduction. In
[Hypoglycemia induced or facilitated by disopyramide].
C Seriès
La Revue de medecine interne, 9(5), 528-529 (1988-11-01)
[Disopyramide, mexiletine, aprindine].
M Suzuki
Nihon rinsho. Japanese journal of clinical medicine, 53 Su Pt 1, 989-993 (1995-02-01)
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