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Merck
CN

B9050

Benoxinate hydrochloride

meets USP testing specifications

Synonym(s):

2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate hydrochloride, 4-Amino-3-butoxybenzoic acid diethylaminoethyl ester, Oxybuprocaine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H28N2O3 · HCl
CAS Number:
5987-82-6
Molecular Weight:
344.88
EC Number:
227-808-8
MDL number:
MFCD00012512
UNSPSC Code:
41116107
PubChem Substance ID:
24892118
NACRES:
NA.21

Key Documents

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Agency

USP/NF
meets USP testing specifications

Quality Level

200

form

solid

application(s)

pharmaceutical (small molecule)

SMILES string

Cl[H].CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI

1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

InChI key

PRGUDWLMFLCODA-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBL6676V
BCBL3297V
BCBL2681V
BCBK9870V
BCBJ3633V

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M M K Muqit et al.
The British journal of ophthalmology, 94(11), 1493-1498 (2010-06-19)
To evaluate pain responses following Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation (PRP). Single-centre randomised clinical trial. 40 eyes of 24 patients with treatment-naive proliferative diabetic retinopathy randomised to 20 and 100 ms PRP under topical 0.4%
Yakov Goldich et al.
Cornea, 30(1), 105-106 (2010-09-18)
To report the diagnosis and management of a patient with chronic ophthalmic topical anesthetic abuse and floppy eyelid syndrome. We describe the case of a 47-year-old man suffering from persistent bilateral ocular irritation and chronic corneal erosions. The patient was
Bingsong Wang et al.
Journal of glaucoma, 24(6), 433-437 (2015-08-01)
To study the association between the insertion location of iris root and narrow angle. This was a prospective observational study. A total of 142 eyes of 142 subjects were recruited, including 78 with narrow angles and 64 normals. All participants
Ching-Hsia Hung et al.
Neuroscience letters, 454(3), 249-253 (2009-05-12)
Proxymetacaine and oxybuprocaine were clinically used for topical ocular anesthesia but never for spinal anesthesia, and therefore spinal anesthetic effects of proxymetacaine and oxybuprocaine were performed and compared with bupivacaine and lidocaine. After rats were injected intrathecally with proxymetacaine, oxybuprocaine
Neal E Mecum et al.
Scientific reports, 10(1), 17225-17225 (2020-10-16)
Lacrimal gland excision (LGE) induced dry eye produces more severe corneal damage in female mice, yet signs of LGE-induced ocular pain and anxiety in male and female mice have not been characterized. Excision of either the extraorbital gland (single LGE)
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