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69480

Supelco

N-Methyl-N-trimethylsilylacetamide

for GC derivatization, LiChropur™, ≥97.0% (GC)

Synonym(s):

MSA

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About This Item

Empirical Formula (Hill Notation):
C6H15NOSi
CAS Number:
7449-74-3
Molecular Weight:
145.27
Beilstein:
506975
EC Number:
231-217-0
MDL number:
MFCD00040758
UNSPSC Code:
12000000
PubChem Substance ID:
329761691
NACRES:
NA.22

grade

for GC derivatization

Quality Level

100

Assay

≥97.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.439

bp

159-161 °C (lit.)

density

0.904 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CN(C(C)=O)[Si](C)(C)C

InChI

1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3

InChI key

QHUOBLDKFGCVCG-UHFFFAOYSA-N

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General description

N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC).

Application

N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following:       
  • Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique.       
  • Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

Other Notes

Powerful silylating agent for polar compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H226

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

118.4 °F - closed cup

Flash Point(C)

48.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB7757

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Cameron J Hunt et al.
Scientific reports, 7(1), 17315-17315 (2017-12-13)
Ferulic acid esterases (FAE, EC 3.1.1.73) cleave the arabinose hydroxycinnamate ester in plant hemicellulose and other related substrates. FAE are commonly categorised as type A-D based on catalytic activities towards model, short alkyl chain esters of hydroxycinnamates. However, this system
Damaged products of cytosine in hydroxyl radical solution under UV-irradiation
Hong J, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 68(2-3), 173-182 (2001)
Mohamed Samy Abd Elaziz et al.
BMC ophthalmology, 19(1), 172-172 (2019-08-09)
To evaluate corneal biomechanical properties by the Ocular Response Analyzer (ORA) in non keratoconic patients underwent penetrating keratoplasty (PK). Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann- correlated intraocular pressure (IOPg), cornea-compensated IOP (IOPcc) using the ORA, and central graft
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