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Merck
CN

14668

Ellagic acid

analytical standard

Synonym(s):

4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase

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About This Item

Empirical Formula (Hill Notation):
C14H6O8
CAS Number:
476-66-4
Molecular Weight:
302.19
Beilstein:
47549
EC Number:
207-508-3
MDL number:
MFCD00006914
UNSPSC Code:
85151701
PubChem Substance ID:
329750574
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤12% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34

InChI

1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

InChI key

AFSDNFLWKVMVRB-UHFFFAOYSA-N

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General description

Ellagic acid is a dimeric derivative of gallic acid. It is a plant polyphenol which has properties like antioxident, anti-inflammatory, anticancer and antiatherosclerosis.

Application

Ellagic acid was used in TLC and RP-HPLC analysis for determination of phytoconstituents content in Root Bark of Oroxylum indicum.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This compound is commonly found in plants of the genus: eucalyptus

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP0076
BCCM4660
BCCL3254
BCCK4071
BCCH9682

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Quantification of baicalein, chrysin, biochanin-A and ellagic acid in root bark of Oroxylum indicum by RP-HPLC with UV detection
Zaveri, Maitreyi, Amit Khandhar, and Sunita Jain
Eurasian Journal of Analytical Chemistry, 245-257 (2008)
Quantification of baicalein, chrysin, biochanin-A and ellagic acid in root bark of Oroxylum indicum by RP-HPLC with UV detection.
Zaveri, Maitreyi, Amit Khandhar, and Sunita Jain.
Eurasian Journal of Analytical Chemistry, 3.2, 245-257 (2008)
Navindra P Seeram et al.
Clinica chimica acta; international journal of clinical chemistry, 348(1-2), 63-68 (2004-09-17)
Ellagic acid (EA) and hydrolyzable ellagitannins (ETs) are dietary polyphenols found in fruits and nuts and implicated with potent antioxidant, anticancer and antiatherosclerotic biological properties. Unfortunately, there are no reports on the bioavailability studies of EA or ETs in the
Felipe Jimenez et al.
The Journal of investigative dermatology, 126(6), 1272-1280 (2006-04-08)
Progressive proteolytic degradation of cutaneous elastic fibers, that cannot be adequately replaced or repaired by adult dermal fibroblasts, constitutes a major feature of aging skin. Our present investigations, employing monolayer cultures of human dermal fibroblasts and organ cultures of skin
J-T Banzouzi et al.
Journal of ethnopharmacology, 81(3), 399-401 (2002-07-20)
Extracts of leaves of Alchornea cordifolia were studied for their antiplasmodial activities. Chloroformic and ether extracts were found to be inactive while the ethanolic extract exhibited mild in vitro activity against Plasmodium falciparum. Fractionation of this extract led us to
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