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Key Documents

Safety Information

407952

Sigma-Aldrich

Ionomycin, Calcium Salt, Streptomyces conglobatus

Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.

Synonym(s):

Ionomycin, Calcium Salt, Streptomyces conglobatus

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20 MG
CN¥1,370.70

CN¥1,370.70


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20 MG
CN¥1,370.70

About This Item

Empirical Formula (Hill Notation):
C41H70O9 · Ca
CAS Number:
Molecular Weight:
747.07
MDL number:
UNSPSC Code:
12352200

CN¥1,370.70


Please contact Customer Service for Availability

Request a Bulk Order

Quality Level

Assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white to off-white

solubility

DMSO: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C41H71O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42,45,48H,12,14-23H2,1-10H3,(H,46,47);/q-1;+2/p-1/b13-11+;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1

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Show Differences

1 of 4

This Item
T2011T2327650357
biological source

chicken egg white

biological source

chicken egg white

biological source

Glycine max (soybean)

biological source

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

form

powder

form

powder

form

lyophilized powder

form

lyophilized solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

water: soluble 10 g/L

solubility

water: soluble 10 g/L

solubility

-

solubility

67 mM potassium phosphate buffer, pH 7.6: 5 mg/mL

mol wt

14 kDa

mol wt

14 kDa

mol wt

-

mol wt

-

General description

Highly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+) and more effective than antibiotic A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, with intense UV absorption. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines. Often used in cell activation experiments when calcium dose-response data is not required.
Useful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Useful in cell activation experiments
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Harmful (C)

Other Notes

Dupuy d′Angeac, A., et al. 1993. J. Cell Physiol.154, 44.
Lee, H.C. 1993. J. Biol. Chem.268, 293.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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