Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

We are planning system maintenance between Friday, Apr 11 at 9:00 PM CDT and Saturday, Apr 12 at 9:00 AM CDT. This will impact both web and offline transactions, including online orders, quotes, price and availability checks, and order status inquiries. We apologize for any inconvenience.

Merck
CN
All Photos(5)

Key Documents

View All Documentation

Safety Information

T2011

Sigma-Aldrich

Trypsin inhibitor

powder

Synonym(s):

Ovomucoid

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

CAS Number:
9035-81-8
EC Number:
232-906-9
MDL number:
MFCD00082102
UNSPSC Code:
12352202
NACRES:
NA.77

Product Name

Trypsin inhibitor from chicken egg white, Type III-O (free of ovoinhibitor)

biological source

chicken egg white

Quality Level

300

type

Type III-O (free of ovoinhibitor)

form

powder

mol wt

27 kDa

solubility

water: soluble 10 g/L

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
OGS47OGS403OGS383
PSF-RSV - RSV PROMOTER PLASMID plasmid vector for molecular cloning

OGS146

PSF-RSV - RSV PROMOTER PLASMID

PSF-SV40 - SV40 PROMOTER PLASMID plasmid vector for molecular cloning

OGS47

PSF-SV40 - SV40 PROMOTER PLASMID

PSF-PGK - PHOSPHOGLYCERATE KINASE PROMOTER PLASMID plasmid vector for molecular cloning

OGS403

PSF-PGK - PHOSPHOGLYCERATE KINASE PROMOTER PLASMID

PSF-CMV-RSV-BLAST ASCI - RSV PROMOTER BLASTICIDIN PLASMID plasmid vector for molecular cloning

OGS383

PSF-CMV-RSV-BLAST ASCI - RSV PROMOTER BLASTICIDIN PLASMID

peptide cleavage

no cleavage

peptide cleavage

no cleavage

peptide cleavage

no cleavage

peptide cleavage

no cleavage

origin of replication

pUC (500 copies)

origin of replication

pUC (500 copies)

origin of replication

pUC (500 copies)

origin of replication

pUC (500 copies)

bacteria selection

kanamycin

bacteria selection

kanamycin

bacteria selection

kanamycin

bacteria selection

kanamycin

mol wt

size 4122 bp

mol wt

size 3867 bp

mol wt

size 4172 bp

mol wt

size 5224 bp

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

General description

Ovomucoid or trypsin inhibitor is an abundant protein in most avian egg whites. The hen′s egg protein is composed of about 186 amino acid residues, and is highly glycosylated. Three tandem domains are each homologous with pancreatic trypsin inhibitor. It is highly immunogenic, and probably accounts for most cases of egg allergy.

Application

Trypsin inhibitor from chicken egg white has been used:
  • to terminate proteolysis reaction[1]
  • in OVO-1 solution to triturate the cell suspension for the dissociation of retina[2]
  • in phosphate buffered saline for dissociation of cortices[3]

Biochem/physiol Actions

Ovomucoid possesses trypsin inhibitor activity. It has several conformational and linear epitopes that can be bound by immunoglobulin E (IgE). It is highly stable against heat and proteolysis.[4]

Unit Definition

One trypsin unit will produce a ΔA253 of 0.001 per min with BAEE as substrate at pH 7.6 at 25 °C; reaction volume 3.2 mL, 1 cm light path.

Other Notes

View more information on Trypsin Inhibitor.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

动植物源性产品

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0000418898
    0000418898
    0000393366
    0000384156
    0000384156

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells
    Jiang HF, et al.
    Journal of virology, 91(12) (2017)
    Meeyong Shin et al.
    Allergy, asthma & immunology research, 5(1), 42-47 (2013-01-02)
    It is known that ovomucoid, an egg allergen, is heat resistant and remains soluble after heating. However, a recent study showed that the antigenic activity of ovomucoid could be reduced by heating when egg white (EW) was mixed with wheat
    Ovomucoid specific immunoglobulin E as a predictor of tolerance to cooked egg
    Bartnikas LM, et al.
    Allergy & rhinology (Providence, R.I.), 6(3), ar-2015 (2015)
    Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential
    Ferree C, et al.
    Faseb Journal (2015)
    Immunopanning purification and long-term culture of human retinal ganglion cells
    Zhang XM, et al.
    Molecular Vision, 16, 2867-2867 (2010)
    View All Related Papers

    Protocols

    Enzymatic Assay of Trypsin Inhibitor

    This technical article described the Enzymatic Assay of Trypsin Inhibitor.

    Chromatograms

    application for HPLC

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service