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858143P

Avanti

18:1 Lyso PS

Avanti Research™ - A Croda Brand

Synonym(s):

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(18:1(9Z)/0:0); 18:1 LPS; C18:1 LPS; 110726

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About This Item

Empirical Formula (Hill Notation):
C24H45NO9PNa
CAS Number:
326589-90-6
Molecular Weight:
545.58
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt)

Assay

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (858143P-10mg)
pkg of 1 × 100 mg (858143P-100mg)
pkg of 1 × 25 mg (858143P-25mg)
pkg of 1 × 5 mg (858143P-5mg)
pkg of 1 × 50 mg (858143P-50mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

Application

18:1 Lyso PS has been used:
  • for the preparation of phospholipid vesicles
  • to study its effects on nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) and serine/threonine-protein kinase (Akt) signals
  • to prevent the lack of de novo synthesis of phosphatidylserine (PS) in Golgi apparatus

Packaging

5 mL Clear Glass Sealed Ampule (858143P-100mg)
5 mL Clear Glass Sealed Ampule (858143P-10mg)
5 mL Clear Glass Sealed Ampule (858143P-25mg)
5 mL Clear Glass Sealed Ampule (858143P-50mg)
5 mL Clear Glass Sealed Ampule (858143P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid
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Cellular Microbiology, 17(10), 1477-1493 (2015)
Suriakarthiga Ganesan et al.
Traffic (Copenhagen, Denmark), 20(3), 226-245 (2018-12-21)
Diacylglycerol (DAG) is a key signaling lipid and intermediate in lipid metabolism. Our knowledge of DAG distribution and dynamics in cell membranes is limited. Using live-cell fluorescence microscopy we investigated the localization of yeast cytosolic-facing pools of DAG in response
Takafumi Matsumura et al.
Scientific reports, 11(1), 3458-3458 (2021-02-12)
In vitro spermatogenesis (IVS) using air-liquid interphase organ culture method is possible with mouse testis tissues. The same method, however, has been hardly applicable to animals other than mice, only producing no or limited progression of spermatogenesis. In the present
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
Wuhanqimuge et al.
FEBS open bio, 3, 243-251 (2013-06-19)
Lysophosphatidylcholine (LPC) is one of the major lysophospholipids mainly generated by phospholipase A2 (PLA2)-mediated hydrolysis of phosphatidylcholine (PC). We previously found that LPC displays neurotrophin-like activity in the rat pheochromocytoma PC12 cells and in cerebellar granule neurons, but the molecular
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