Skip to Content
Merck
CN

850092P

Avanti

Brain Lyso PS

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-lysophosphatidylserine (Brain, Porcine) (sodium salt)

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

CAS Number:
383907-66-2
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Brain Lyso PS, Avanti Research™ - A Croda Brand 850092P, powder

InChI

1S/C24H48NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29;/h21-22,26H,2-20,25H2,1H3,(H,28,29)(H,30,31);/q;+1/p-1/t21-,22+;/m1./s1

InChI key

SVSJEWKLQKWQOV-NSLUPJTDSA-M

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

assay

>99% (LPS; may contain up to 10% of the 2-LPS isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (850092P-10mg)
pkg of 1 × 5 mg (850092P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850092P

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application

Brain Lyso PS is suitable for use:
  • as standard to quantify lipids using ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
  • in the preparation of liposomes for coating dynabeads for binding of factor H (fH)
  • as a ligand for G-protein coupled receptor 34 (GPR34) in in vitro experiments to investigate its effect granulosa cells(GC) and hormone production
  • as substrate for sicariid phospholipase D (PLD) toxins (SicTox) enzymes

Biochem/physiol Actions

Lyso-Phosphatidylserine (Lyso-PS) plays a key role in histamine release from mast cells. Lyso-PS inhibits the growth to T cells. It is a chemotactic substance for fibroblast and tumor cells. Lyso-PS is involved in tumor progression and allergic reactions.

General description

Lyso-phosphatidylserine (lyso-PS) is produced by the enzymatic action of phospholipase A1 and A2 on phosphatidylserine.

Packaging

5 mL Amber Glass Screw Cap Vial (850092P-10mg)
5 mL Amber Glass Screw Cap Vial (850092P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells
Li L, et al.
Journal of Chromatography A, 1381(3), 140-148 (2015)
G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications
Spicer LJ, et al.
Domestic Animal Endocrinology, 59(6), 90-99 (2017)
Altered immune response in mice deficient for the G protein-coupled receptor GPR34
Liebscher I, et al.
Test, 286(3), 2101-2110 (2011)
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells
Leffler J, et al.
Test, 285(6), 3766-3776 (2010)
Lysophosphatidylserine stimulates chemotactic migration of colorectal cancer cells through GPR34 and PI3K/Akt pathway
Iida Y, et al.
Anticancer Research, 34(10), 5465-5472 (2014)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service