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438227

Sigma-Aldrich

Hydroxylamine solution

50 wt. % in H2O

Synonym(s):

HDA

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250 ML
CN¥521.56
1 L
CN¥1,650.59

CN¥521.56

Estimated to ship onMay 26, 2025Details

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250 ML
CN¥521.56
1 L
CN¥1,650.59

About This Item

Linear Formula:
NH2OH
CAS Number:
7803-49-8
Molecular Weight:
33.03
EC Number:
232-259-2
MDL number:
MFCD00044522
UNSPSC Code:
12352116
PubChem Substance ID:
24867438
NACRES:
NA.22

CN¥521.56

Estimated to ship onMay 26, 2025Details

Request a Bulk Order

vapor pressure

9 mmHg ( 40 °C)

Quality Level

200

form

liquid

concentration

50 wt. % in H2O

bp

>100 °C

mp

8 °C (46 °F)

solubility

water: soluble

density

1.078 g/mL at 25 °C

storage temp.

room temp

SMILES string

NO

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68250114510195073
Methyl orange solution 0.1% indicator pH 3.1-4.4 (red yellow-orange)

101323

Methyl orange solution 0.1%

甲基橙 for microscopy (Hist.), indicator (pH 3.0-4.4)

68250

甲基橙

甲基橙 ACS reagent, Dye content 85 %

114510

甲基橙

Mordant Orange 1 Dye content 70 %

195073

Mordant Orange 1

storage temp.

15-25°C

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

density

1.00 g/cm3 at 20 °C

density

-

density

-

density

-

pH

6 (20 °C in H2O)

pH

3.0-4.4, pink to yellow

pH

3.0-4.4, pink to yellow

pH

-

General description

Hydroxylamine is a weak base[1] that is mainly used as a reducing agent in organic reactions.[2]

Application

Reactant for preparation of:
  • Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)
  • Hydroxyaminoguanidines as anti-cancer agents
  • Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation
  • Carboxamide derivatives of ofloxacin with improved antimicrobial properties
  • Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors
  • HIV integrase inhibitors

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Target Organs

Blood, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    STBL2395
    STBL1558
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    STBK7962

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    Ian R Kelsall et al.
    Proceedings of the National Academy of Sciences of the United States of America, 116(27), 13293-13298 (2019-06-19)
    The linear ubiquitin assembly complex (LUBAC) comprises 3 components: HOIP, HOIL-1, and Sharpin, of which HOIP and HOIL-1 are both members of the RBR subfamily of E3 ubiquitin ligases. HOIP catalyses the formation of Met1-linked ubiquitin oligomers (also called linear
    Assembly of cyclic peptide dendrimers from unprotected linear building blocks in aqueous solution.
    DavidaPallin T.
    Chemical Communications (Cambridge, England), 11, 1345-1346 (1996)
    Reducing graphene oxide via hydroxylamine: a simple and efficient route to graphene.
    Zhou X, et al.
    The Journal of Physical Chemistry C, 115(24), 11957-11961 (2011)
    Elie Akanny et al.
    Analytical and bioanalytical chemistry, 411(21), 5563-5576 (2019-06-19)
    The Surface-enhanced Raman spectroscopy (SERS) method based on gold nanoparticles as SERS substrate was investigated for the label-free detection and quantification of probiotic bacteria that are widely used in various pharmaceutical formulations. Indeed, the development of a simple and fast
    Rika Goda et al.
    Drug metabolism and disposition: the biological fate of chemicals, 34(5), 828-835 (2006-03-02)
    Flutamide (2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide), a nonsteroidal antiandrogen, is used in the treatment of prostate cancer but is occasionally associated with hepatic dysfunction. In the present study, the metabolism of flutamide including the formation of the possible reactive toxic metabolites was investigated using
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