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E3876

Sigma-Aldrich

N-Ethylmaleimide

crystalline, ≥98% (HPLC)

Synonym(s):

NEM

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200 EA
CN¥2,578.76

CN¥2,578.76

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200 EA
CN¥2,578.76

About This Item

Empirical Formula (Hill Notation):
C6H7NO2
CAS Number:
128-53-0
Molecular Weight:
125.13
Beilstein:
112448
EC Number:
204-892-4
MDL number:
MFCD00005509
UNSPSC Code:
12352106
PubChem Substance ID:
24278420
NACRES:
NA.21

CN¥2,578.76

Please contact Customer Service for Availability
Request a Bulk Order

biological source

synthetic (organic)

Quality Level

200

Assay

≥98% (HPLC)

form

crystalline

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. )

technique(s)

activity assay: suitable
co-immunoprecipitation (co-IP): suitable
immunoblotting: suitable

color

white to faint yellow

bp

210 °C (lit.)

mp

43-46 °C (lit.)

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faint yellow or tan

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1 of 4

This Item
M265955129580038
2,4,6-Triamino-1,3,5-triazine for synthesis

808614

2,4,6-Triamino-1,3,5-triazine

Melamine 99%

M2659

Melamine

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine 97%

551295

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine

Melamine-(triamine-15N3) analytical standard

80038

Melamine-(triamine-15N3)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

mp

354 °C (decomposition)

mp

>300 °C (lit.)

mp

223-227 °C (lit.)

mp

>300 °C (lit.)

density

1.57 g/cm3 at 20 °C

density

-

density

-

density

-

bp

>354 °C/1013 hPa (sublimed)

bp

-

bp

-

bp

-

form

powder

form

powder

form

-

form

-

Application

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Preparation Note

NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H300,H311,H314,H317

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

163.2 °F - closed cup

Flash Point(C)

72.9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000433210
    0000433209
    0000433209
    0000433210
    WXBF5211V

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