Skip to Content

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
All Photos(4)

Key Documents

View All Documentation

I1149

Sigma-Aldrich

Iodoacetamide

BioUltra

Synonym(s):

2-Iodoacetamide, Monoiodoacetamide, alpha-Iodoacetamide

Sign Into View Organizational & Contract Pricing

Select a Size

1 KG
CN¥407.32
5 KG
CN¥2,582.22

CN¥407.32

List PriceCN¥1,357.73Save 70%

Estimated to ship onJune 25, 2025Details

Request a Bulk Order
All Photos(4)

Select a Size

Change View
1 KG
CN¥407.32
5 KG
CN¥2,582.22

About This Item

Linear Formula:
ICH2CONH2
CAS Number:
144-48-9
Molecular Weight:
184.96
Beilstein:
1739080
EC Number:
205-630-1
MDL number:
MFCD00008028
UNSPSC Code:
12352202
PubChem Substance ID:
24278486
NACRES:
NA.77

CN¥407.32

List PriceCN¥1,357.73Save 70%

Estimated to ship onJune 25, 2025Details

Request a Bulk Order

biological source

synthetic (organic)

Quality Level

300

product line

BioUltra

Assay

≥99% (NMR)

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

92-95 °C (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
T046730610H100
睾酮-2,3,4-13C3 溶液 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

T070

睾酮-2,3,4-13C3 溶液

睾酮-D3标准液 CRM 溶液 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

T046

睾酮-D3标准液 CRM 溶液

睾丸激素-2,3,4-13C3 溶液 0.1 mg/mL in methanol, 99 atom % 13C, 98% (CP)

730610

睾丸激素-2,3,4-13C3 溶液

17α-羟孕酮-13C3标准液 溶液 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H100

17α-羟孕酮-13C3标准液 溶液

application(s)

clinical testing

application(s)

clinical testing

application(s)

-

application(s)

clinical testing
clinical testing

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

form

liquid

form

liquid

form

solution

form

liquid

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

300

grade

certified reference material

grade

certified reference material

grade

-

grade

certified reference material

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

Iodoacetamide has been used:
  • in protein digestion for proteomic analysis
  • to alkylate protein samples
  • in the denaturation of cow′s milk allergens, β-lactoglobulin (BLG) and α-lactalbumin (ALA)

Biochem/physiol Actions

Iodoacetamide (IAA) is used to inhibit glycolysis due to its ability to irreversibly inhibit the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). IAA is used to investigate the role of cysteine residues in enzyme catalysis and the brain cell transport process. It can react with low molecular weight thiol compounds like mercaptoethanol and glutathione. IAN may also block enzymes like bromelain, cathepsin C, clostripain, and carboxypeptidase P.
Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H317,H334,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0000409416
    0000409416
    0000409427
    0000394671
    0000394663

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Tommy Weiss-Sadan et al.
    Theranostics, 9(20), 5731-5738 (2019-09-20)
    Despite the common use of lipid-lowering medications, cardiovascular diseases continue to be a significant health concern. Atherosclerosis, one of the most frequent causes of cardiovascular morbidity, involves extensive inflammatory activity and remodeling of the vascular endothelium. This relentless inflammatory condition
    Mirko Zaffagnini et al.
    Antioxidants & redox signaling, 16(1), 17-32 (2011-06-29)
    Cysteines (Cys) made acidic by the protein environment are generally sensitive to pro-oxidant molecules. Glutathionylation is a post-translational modification that can occur by spontaneous reaction of reduced glutathione (GSH) with oxidized Cys as sulfenic acids (-SOH). The reverse reaction (deglutathionylation)
    Konstantinos Boulias et al.
    Molecular cell, 75(3), 631-643 (2019-07-08)
    mRNAs are regulated by nucleotide modifications that influence their cellular fate. Two of the most abundant modified nucleotides are N6-methyladenosine (m6A), found within mRNAs, and N6,2'-O-dimethyladenosine (m6Am), which is found at the first transcribed nucleotide. Distinguishing these modifications in mapping
    Valentina R Minciacchi et al.
    Oncotarget, 6(13), 11327-11341 (2015-04-11)
    Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
    Elena B Lugli et al.
    Arthritis research & therapy, 17, 9-9 (2015-01-21)
    Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without
    View All Related Papers

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service