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202509

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average Mn 2,000, methoxy, hydroxyl

Synonym(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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100 ML
CN¥594.19
500 ML
CN¥849.08
1 L
CN¥1,250.63

CN¥594.19

Estimated to ship onApril 07, 2025Details

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100 ML
CN¥594.19
500 ML
CN¥849.08
1 L
CN¥1,250.63

About This Item

Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
9004-74-4
MDL number:
MFCD00084416
UNSPSC Code:
12162002
PubChem Substance ID:
24852095
NACRES:
NA.23

CN¥594.19

Estimated to ship onApril 07, 2025Details

Request a Bulk Order

Product Name

Poly(ethylene glycol) methyl ether, average Mn ~2,000

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

form

flakes (or pellets)

mol wt

average Mn ~2,000

viscosity

54.6 cSt(210 °F)(lit.)

transition temp

Tm 52 °C

functional group

hydroxyl

SMILES string

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

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Show Differences

1 of 4

This Item
48900W0625861375
May-Grünwald solution

63590

May-Grünwald solution

Giemsa Stain, Modified Solution (for the staining (of cellular blood components and blood parasites))

48900

Giemsa Stain, Modified Solution

Wright stain suitable for blood stain

W0625

Wright stain

Wright stain certified by the BSC

861375

Wright stain

suitability

Chlamydia spp., Plasmodium spp., bacteria, spirochetes, Histoplasma spp., protozoa, Trichomonas spp.

suitability

Chlamydia spp., Histoplasma spp., Plasmodium spp., Trichomonas spp., bacteria, protozoa, spirochetes

suitability

-

suitability

-

grade

for the staining of blood constituents

grade

-

grade

-

grade

certified by the Biological Stain Commission

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

density

0.80 g/mL at 20 °C

density

-

density

-

density

-

impurities

methanol

impurities

-

impurities

-

impurities

-

General description

It is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether. Etherification of the PEG chain ends can be undertaken in basic conditions by reacting it with alkyl halides. mPEG can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.

Application

Poly(ethylene glycol) methyl ether-attached dendrimers can be used as carriers for anticancer drugs. This novel drug carrier has a biocompatible surface and an interior for the encapsulation of drugs.

It can be used as a pore-forming agent in the preparation of ultrafiltration membranes which are used in the removal of macromolecules.

It can also be used as a starting material in the preparation of a biodegradable amphiphilic copolymer of poly(L-alanine) with mPEG.

Features and Benefits

Inserting poly(ethylene glycol) methyl ether (mPEG) side chain enhances the hydrophilicity and flexibility of the polymer matrix.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000197564
    0000197564
    0000338361
    MKCV6083
    MKCV9757

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    Prakash G Avaji et al.
    Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
    Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
    Yi Wei et al.
    Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
    The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
    Seung-Young Lee et al.
    Biomaterials, 34(2), 552-561 (2012-10-20)
    Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
    Mulu Z Tesfay et al.
    Journal of virology, 87(7), 3752-3759 (2013-01-18)
    We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
    Junming Li et al.
    Journal of biomedical nanotechnology, 8(5), 809-817 (2012-08-15)
    In this study, quercetin (QC) with cancer chemoprevention effect and anticancer potential was loaded into polymeric micelles of methoxy poly(ethylene glycol)-cholesterol conjugate (mPEG-Chol) in order to increase its water solubility. MPEG-Chol with lower critical micelle concentration (CMC) value (4.0 x
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