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81323

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 5,000, methoxy, hydroxyl

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Synonym(s):
Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

vapor pressure

0.05 mmHg ( 20 °C)

form

flakes
powder or crystals

mol wt

average Mn 5,000

mp

60-64 °C

Ω-end

hydroxyl

α-end

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Application

Poly(ethylene glycol) methyl ether (mPEG) is a hydrophilic polymer that is used to control the flexibility of a composite. mPEG can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.

Other Notes

Polymer used in the polymer-supported liquid synthesis of oligosaccharides

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Kangan Li et al.
International journal of nanomedicine, 8, 2589-2600 (2013-07-28)
Development of dual-mode or multi-mode imaging contrast agents is important for accurate and self-confirmatory diagnosis of cancer. We report a new multifunctional, dendrimer-based gold nanoparticle (AuNP) as a dual-modality contrast agent for magnetic resonance (MR)/computed tomography (CT) imaging of breast
Hamed Nosrati et al.
Pharmaceutical development and technology, 24(1), 89-98 (2018-01-09)
In this study, we designed a polymersome system for the controlled release of methotrexate (MTX) as an anticancer drug with the objective of improving the loading efficiency of the drug in polymersomes as well as achievement of an efficient control
Yvonne K Girard et al.
PloS one, 8(10), e75345-e75345 (2013-10-23)
The development of a suitable three dimensional (3D) culture system for anticancer drug development remains an unmet need. Despite progress, a simple, rapid, scalable and inexpensive 3D-tumor model that recapitulates in vivo tumorigenesis is lacking. Herein, we report on the
Magnetite nanoparticles stabilized with polymeric bilayer of poly (ethylene glycol) methyl ether-poly (?-caprolactone) copolymers
Meerod S, et al.
Polymer, 49(18), 3950-3956 (2008)
S.P. Douglas et al.
Journal of the American Chemical Society, 113, 5095-5095 (1991)

Articles

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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