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Merck
CN

TTR

transthyretin

别名:
CTS, CTS1, HsT2651, PALB, TBPA
物种:
UniProtKB ID:
基因ID:
  • Human(7276) Summary: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
  • Mouse(22139) transthyretin
  • Rat(24856) transthyretin
  • fruit fly(246932) tetrapter
  • chicken(396277) transthyretin
  • Zebrafish(449556) transthyretin (prealbumin, amyloidosis type I)
  • domestic cat(101085927) transthyretin
  • dog(480167) transthyretin
  • cow(280948) transthyretin
  • sheep(443389) transthyretin
  • domestic guinea pig(100735950) transthyretin
  • naked mole-rat(101726783) transthyretin

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Small Molecule - Antagonist

货号
说明
物种
二苯醚, ReagentPlus®, ≥99%,
物种
human
二苯醚, ≥99%, FG,
物种
human
N-苯基邻氨基苯甲酸, 98%,
物种
human
二苯醚, ReagentPlus®, 99%,
物种
human
尼群地平, >95%, powder,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
抗-TTR 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TTR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0290, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-TTR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
immunohistochemistry
Anti-Transthyretin Antibody, clone 7G8-E11-E7, clone 7G8-E11-E7, from mouse,
物种反应性
human
应用
ELISA
western blot
Anti-Transthyretin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

货号
说明
物种
前白蛋白 来源于人类血浆, lyophilized powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TTR,
物种
human
MISSION® esiRNA, targeting mouse Ttr,
物种
mouse