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Merck
CN

P1742

前白蛋白 来源于人类血浆

lyophilized powder

别名:

甲状腺素结合前白蛋白, 甲状腺素运载蛋白

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关于此项目

化学文摘社编号:
87090-18-4
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
MFCD00132069

主要文件

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产品名称

前白蛋白 来源于人类血浆, lyophilized powder

biological source

human plasma

assay

≥95% (SDS-PAGE)

form

lyophilized powder

technique(s)

immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable

impurities

Infectious agents, tested

solubility

H2O: soluble 1 mg/mL

ε (extinction coefficient)

13.5 at 280 nm at 1%

UniProt accession no.

P02766

storage temp.

−20°C

Quality Level

200

Gene Information

human ... TTR(7276)

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相关类别

Application

人前白蛋白用于研究肺癌血清中甲状腺素运载蛋白表达的下调。
前白蛋白（来自人血浆）已用作免疫沉淀的阳性对照作为火箭免疫电泳法定量分析脑脊液的参考标准品。

Biochem/physiol Actions

人前白蛋白可在类癌瘤中观察到。
前白蛋白水平是营养不良的指示剂，而且可能受到炎症反应调节。在慢性肾衰竭患者的透析期间，它被视为蛋白质能量营养不良(PEM)的潜在标志物。低水平的前蛋白会导致心脏衰竭(HF)风险提高。

General description

人前白蛋白是18号染色体的产物。它是一种血清蛋白，主要在肝脏中合成。 它是一种四聚体蛋白，分子量为55 kDa。人前白蛋白由非共价结合的四个相同的单体（127个氨基酸残基）组成，排列成对称的四面体。

Packaging

包装规格基于蛋白含量

Physical form

含有磷酸钠和NaCl的冻干粉

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000507926
0000507926
0000496720
0000496720
0000497072

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molecular weight of Product P1742, Prealbumin from human plasma?

    The molecular weight has been reported to be 54,980 Daltons. Referece: The Plasma Proteins, 2nd edition (1975) p. 60.

  6. What is the volume from which Product P1742, Prealbumin from human plasma, is lyophilized from?

    The starting volume is lot specific. Please contact Technical Service to obtain the exact volume of your lot of interest.

  7. What is the solubility of Product P1742, Prealbumin from human plasma?

    This product is soluble in water at 1mg/mL.

  8. What is the purity of Product P1742, Prealbumin from human plasma?

    Information about purity can be found on the lot specific certificate of analysis.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Gen Sobue
Rinsho shinkeigaku = Clinical neurology, 43(11), 769-774 (2004-05-22)
A nationwide study of CMT and FAP has been performed. In FAP TTR Met30 families with late onset, neuropathy showed male preponderance, low penetrance, little relationship to endemic foci, sensorimotor symptoms beginning distally in the lower extremities with disturbance of
J Figueras et al.
Medicina clinica, 116(10), 377-379 (2001-05-03)
Domino or sequential liver transplantation (DTXL) is a kind of living donor transplant, which was proposed in 1993 and performed for the first time in 1995; later on, more than 45 have been reported. The liver from a patient with
Minori Kodaira et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 18(1), 10-18 (2011-01-26)
The process of deterioration of peripheral nerve function in familial amyloid polyneuropathy (FAP) with amyloidogenic transthyretin (ATTR) Val30Met has not been systematically evaluated hitherto. We performed nerve conduction studies in 69 patients with FAP with ATTR Val30Met from one of
David Adams et al.
Presse medicale (Paris, France : 1983), 41(9 Pt 1), 793-806 (2012-02-22)
The treatment of familial amyloid polyneuropathies (FAP) is complex and requires a neurological and cardiological multidisciplinary coverage. It includes specific treatments to control the progression of the systemic amyloidogenesis, the symptomatic treatment of the peripheral and autonomic neuropathy (digestive, urinary
J P Hegmann
Behavior genetics, 9(3), 165-175 (1979-05-01)
Behavioral and physiological scores from 697 mice sampled from lines at various times during their response to bidirectional selection for divergent caudal nerve conduction velocity suggest broad-reaching behavioral effects of the gene differences among lines. Sciatic nerve conduction velocity differences
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