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Merck
CN

SCNN1B

sodium channel, non-voltage-gated 1, beta subunit

Synonyms:
BESC1, ENaCb, ENaCbeta, SCNEB
Species:
Human SCNN1B (6338), Mouse Scnn1b (20277), Rat Scnn1b (24767), chicken SCNN1B (427673), dog SCNN1B (489972), Horse SCNN1B (100069008), domestic cat SCNN1B (101099767), cow SCNN1B (533355), sheep SCNN1B (100170325), Goat SCNN1B (100861026) ...More
UniProtKB ID:
P51168, C5HTZ2, O60891, Q96KG2, Q9UJ32, Q9UMU5
Gene ID:
  • Human(6338) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Mouse(20277) sodium channel, nonvoltage-gated 1 beta
  • Rat(24767) sodium channel, nonvoltage-gated 1, beta
  • chicken(427673) sodium channel, non-voltage-gated 1, beta subunit
  • dog(489972) sodium channel, non-voltage-gated 1, beta subunit
  • Horse(100069008) sodium channel, non-voltage-gated 1, beta subunit
  • domestic cat(101099767) sodium channel, non-voltage-gated 1, beta subunit
  • cow(533355) sodium channel, nonvoltage-gated 1, beta
  • sheep(100170325) sodium channel, non-voltage-gated 1, beta subunit
  • Goat(100861026) sodium channel, non-voltage-gated 1, beta subunit
  • Domestic Rabbit(100009564) sodium channel, non-voltage-gated 1, beta subunit
  • domestic guinea pig(100270805) sodium channel, nonvoltage-gated 1 beta
  • naked mole-rat(101717352) sodium channel, non-voltage-gated 1, beta subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4504262
Anti-phospho-Nonvoltage-gated Sodium Channel 1 (pThr615) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB5201792
Monoclonal Anti-ENaC beta-Atto 594 antibody produced in mouse, clone 7B8,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
SAB5201798
Monoclonal Anti-ENaC beta-Allophycocyanin antibody produced in mouse, clone 7B8,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
SAB5201819
Monoclonal Anti-ENaC beta-Horseradish Peroxidase antibody produced in mouse, clone 16E4,
Species Reactivity
mouse
Application
western blot
SAB5201789
Monoclonal Anti-ENaC beta-Atto 390 antibody produced in mouse, clone 7B8,
Species Reactivity
mouse
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
A5585
5-(N-Methyl-N-isobutyl)­amiloride, ≥98% (TLC), powder,
Species
mouse, rat, human
B2417
Benzamil hydrochloride hydrate, ≥98% (HPLC),
Species
mouse, rat, human
A4562
5-(N,N-Dimethyl)amiloride hydrochloride, ,
Species
rat, mouse, human

esiRNA

Product Number
Description
Species
EHU066451
MISSION® esiRNA, targeting human SCNN1B,
Species
human