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Merck
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MMP9

matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Synonyms:
CLG4B, GELB, MANDP2, MMP-9
Species:
UniProtKB ID:
Gene ID:
  • Human(4318) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
  • Mouse(17395) matrix metallopeptidase 9
  • Rat(81687) matrix metallopeptidase 9
  • Domestic Rabbit(100008993) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • sheep(100192422) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • dog(403885) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic cat(101084185) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • cow(282871) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic guinea pig(100728510) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • chicken(395387) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Horse(100169862) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • naked mole-rat(101717243) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Zebrafish(406397) matrix metalloproteinase 9
  • Horse(100056599) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

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ELISA

Product Number
Description
Species
Rhesus Macaque MMP-9 ELISA, for serum, plasma and cell culture supernatants,
Species
rat
Human MMP-9 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Rabbit MMP-9 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
domestic rabbit
Mouse pro-MMP-9 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Matrix Metalloproteinase-9 antibody produced in goat, affinity isolated antibody,
Species Reactivity
mouse
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MMP9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-MMP-9 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-MMP9 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-MMP9 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
α-Sexithiophene, ,
Species
human, rat
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse

Proteins

Product Number
Description
Species
MMP-9, human, proform, ,
Species
human
Matrix Metalloproteinase-9 human, recombinant, >90% (SDS-PAGE), buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP9,
Species
human
MISSION® esiRNA, targeting mouse Mmp9,
Species
mouse