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Merck
CN
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安全信息

M8945

Sigma-Aldrich

基质金属蛋白酶-9 人

recombinant, >90% (SDS-PAGE), buffered aqueous solution

别名:

基质金属蛋白酶-9, 明胶酶B, 明胶酶，95 kDa

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About This Item

MDL编号:
MFCD01323840
UNSPSC代码:
12352204
NACRES:
NA.32

质量水平

200

检测方案

>90% (SDS-PAGE)

形式

buffered aqueous solution

分子量

apparent mol wt ~93 kDa

UniProt登记号

P14780

运输

dry ice

储存温度

−70°C

基因信息

human ... MMP9(4318)

生化/生理作用

MMP-9 降解构成胞外基质的胶原蛋白，在控制血管生成中起作用。

外形

Tris-HCl、pH 7.5、氯化钙、氯化钠和Brij-35中的溶液

分析说明

根据其切割荧光肽底物的能力来测量生物活性。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molecular weight of product M8945 (Matrix Metalloproteinase-9 Human)

    Human MMP-9 consists of a 688 amino acid residue recombinant protein which has a predicted molecular mass of approximately 77 kDa. By SDS-PAGE the apparent molecular mass is approximately 93 kDa.

  6. Does product M8945 (Matrix Metalloproteinase-9 Human) need to be activated?

    To activate recombinant human MMP-9, prepare a p-aminophenylmercuric acetate (APMA) solution in DMSO. Add the AMPA solution to the MMP-9 to a final APMA concentration of 1 mM. Incubate at 37°C. for 16 - 24 hours.

  7. Is product M8945 (Marix Metalloproteinase-9 Human) endotoxin free?

    This product contains < 1.0 EU/ug of the enzyme.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Carla Graça et al.
Foods (Basel, Switzerland), 9(10) (2020-10-07)
The influence of flour replacement by yogurt or curd-cheese additions (from 10% to 20%, w/w) on the glycemic response and bioactivity improvements of gluten-free bread was evaluated. Starch digestibility, measured by an in vitro digestion model, was applied to determine
Gelatinase B
Collier, I.E., and Goldberg, G.I. et al.
Handbook of Proteolytic Enzymes, 1205-1210 (1998)
S Chandler et al.
Neuroscience letters, 201(3), 223-226 (1995-12-15)
Matrix metalloproteinases (MMPs) are a group of enzymes responsible for the degradation of interstitial connective tissue and basement membrane. The coding sequences for five of the human MMPs, viz. interstitial collagenase, 72 kDa gelatinase, stromelysin-1, matrilysin and 92 kDa gelatinase
Marcelo Rodríguez-Piñón et al.
Anatomia, histologia, embryologia, 48(4), 306-314 (2019-03-25)
The tortuous nature of the ovine cervix restricts the transcervical passage of the cannula, and many studies have aimed to understand the endocrine mechanism of the remodelling of cervical tissue in adult ewe. However, little is known about the remodelling
Wei-Li Hsu et al.
BMC veterinary research, 10, 202-202 (2014-08-28)
Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for the early prediction of renal diseases. NGAL may exist as monomer, dimer and/or NGAL/MMP-9 complex forms in humans. In this study, the existence of various forms of NGAL in urine (uNGAL)
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