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生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse
技术
immunohistochemistry: 5-15 μg/mL using cells or tissues
immunoprecipitation (IP): 25 μg/mL using conditioned media of transfected NSO cells
western blot: 0.25 μg/mL
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
mouse ... Mmp9(17395)
一般描述
Matrix metalloproteinase-9 (MMP-9) is a pro-inflammatory, zinc-dependent proteinase which is also known as 92kDa gelatinase. It is produced by various cells like granulocytes and mononuclear cells. The gene encoding it is localized on human chromosome 20q11.2-q13.1.
特异性
This antibody recognizes pro and active mouse MMP-9. Immunoblotting and ELISA applications show an ~10% cross-reactivity with recombinant human MMP-9.
免疫原
purified, NSO-derived, recombinant mouse matrix metalloproteinase-9.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
生化/生理作用
Matrix metalloproteinase-9 (MMP-9) has been studied as a biomarker of nervous tissue inflammation in multiple sclerosis (MS).
目标描述
Matrix Metalloproteinase-9 encodes an enzyme that degrades type IV and V collagens.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Nina Nguon et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 22(2), 272-280 (2014-03-19)
Data on the toxicity of lewisite (L), a vesicant chemical warfare agent, are scarce and conflicting, and the use of the specific antidote is not without drawbacks. This study was designed to evaluate if the SKH-1 hairless mouse model was
Cécile Cléry-Barraud et al.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 19(1), e146-e156 (2012-06-30)
To date, sulphur mustard (SM) cutaneous toxicity has been commonly assessed on account of several animal models such as pigs and weanling pigs. Few experiments however, have been carried out on mice so far. In this study, we aimed at
Beate Fisslthaler et al.
International journal of molecular sciences, 20(12) (2019-06-30)
The AMP-activated protein kinase (AMPK) is an energy sensing kinase that is activated by a drop in cellular ATP levels. Although several studies have addressed the role of the AMPKα1 subunit in monocytes and macrophages, little is known about the
Senem Maral et al.
Medicine, 94(16), e732-e732 (2015-04-24)
Chronic myeloproliferative disorders such as polycythemia vera (PV), essential thrombocytosis (ET), and idiopathic myelofibrosis arise from clonal proliferation of neoplastic stem cells in the bone marrow. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have potential to degrade
Xiaoli Zhang et al.
Medical science monitor : international medical journal of experimental and clinical research, 21, 1115-1123 (2015-04-22)
The role of matrix metalloproteinase 9 (MMP-9) polymorphisms in breast cancer risk remains unclear. The purpose of this study was to evaluate the association between MMP-9 variants and breast cancer susceptibility. Case-control studies were searched on electronic databases to retrieve
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