跳转至内容
Merck
CN

CTSB

cathepsin B

别名:
APPS, CPSB
物种:
UniProtKB ID:
基因ID:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • domestic guinea pig(100714169) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • dog(486077) cathepsin B
  • Horse(100060963) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • sheep(780470) cathepsin B
  • chicken(396329) cathepsin B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
物种反应性
bovine, human, porcine
应用
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
物种反应性
human
应用
immunohistochemistry
western blot
Monoclonal Anti- Cathepsin B 小鼠抗, clone CB59-4B11, purified from hybridoma cell culture,
物种反应性
human, rat
应用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
物种
human
MG-132(R), ≥95% (HPLC),
物种
human
钙蛋白酶抑制剂I, ≥97% (TLC), powder,
物种
human
N-氰基二乙基胺, 99%,
物种
human

Proteins

货号
说明
物种
组织蛋白酶B 来源于人类肝脏, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
物种
human
组织蛋白酶B 来源于牛脾脏, lyophilized powder, ≥10 units/mg protein,
物种
cow
组织蛋白酶B 来源于人类胎盘, lyophilized powder, ≥5 units/mg protein,
物种
human
Cathepsin B Active 人, recombinant, expressed in FreeStyle 293-F cells, ≥90% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ctsb,
物种
mouse
MISSION® esiRNA, targeting human CTSB,
物种
human

Small Molecule - Substrate

货号
说明
物种
Z-精氨酸-精氨酸-7-酰氨基-4-甲基香豆素 盐酸盐, ,
物种
mouse, human, rat