跳转至内容
Merck
CN

C2211

Sigma-Aldrich

Z-Leu-Leu-Leu-al

≥90% (HPLC)

别名:

MG-132

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C26H41N3O5
分子量:
475.62
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.32

product name

Z-Leu-Leu-Leu-al, ≥90% (HPLC)

质量水平

检测方案

≥90% (HPLC)

形式

powder

颜色

white

溶解性

DMSO: soluble

储存温度

−20°C

SMILES字符串

[H]C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI

1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1

InChI key

TZYWCYJVHRLUCT-VABKMULXSA-N

基因信息

正在寻找类似产品? 访问 产品对比指南

Amino Acid Sequence

Z-Leu-Leu-Leu-al

应用

Z-Leu-Leu-Leu-al或MG132,已被用作蛋白酶体抑制剂。它还被用于测试海胆胚胎中的泛素化和类泛素化途径。

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How should Product C2211, Z-Leu-Leu-Leu-al, be dissolved?

    MG132 is soluble in DMSO or at 10 mg/mL in a chloroform:methanol solution (95:5). We test the solubility at 1 mg/mL in methanol.

  4. What is the solution stability of MG132, Product C2211, Z-Leu-Leu-Leu-al?

    This product can be stored in aliquots at -20°C for up to one month.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client*
Johannes W. Bigenzahn
Molecular and Cellular Proteomics (2016)
Vaino K. Hopsu-Havu, Mikko Jarvinen, Heidrun Kirschke
Proteolysis in Cell Functions (1997)
MG132, a proteasome inhibitor, induced death of calf pulmonary artery endothelial cells via caspase-dependent apoptosis and GSH depletion.
Anticancer Research (2010)
Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-? levels in brain
Benjamin W
Journal of Neurochemistry (2016)
Proteasome inhibitors: from research tools to drug candidates
Alexei F.Kisselev
Chemistry and Biology, 8(8), 739-758 (2001)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门