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Merck
CN

I4506

IgG 来源于人类血清

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

别名:

人 IgG

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Technique(s):
ELISA: suitable, dot immunobinding: suitable, immunoelectrophoresis: suitable, western blot: suitable
Application:
DIBA, ELISA, IEP, WB
Citations:
228
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conjugate

unconjugated

Quality Level

grade

reagent grade

assay

≥95% (SDS-PAGE)

form

essentially salt-free, lyophilized powder

composition

Protein, ≥90%

technique(s)

ELISA: suitable, dot immunobinding: suitable, immunoelectrophoresis: suitable, western blot: suitable

storage temp.

2-8°C

General description

纯化人IgG由混合的正常人血清经过分级分离和离子交换层析获得。本品以基本不含盐(不到1%钠)的冻干粉形式提供。

Application

以人血清IgG为标准品,在ELISA法测定中采用浓度为1.274 mg/ml, 检测牙 龈卟啉单胞菌间质普雷沃氏菌的抗体反应。它被用在0.2 mg/ml浓度时对Vero、BHK、PtK2细胞的免疫标记。人血清IgG被用作抗-志贺氏菌 LPS抗体的SDS-PAGE的标准品。

Biochem/physiol Actions

IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它是由B细胞分泌的,存在于血液和细胞外液体中,可以防止细菌、真菌和病毒引起的感染。母体IgG通过胎盘传递给胎儿,该过程对新生儿免疫防御感染至关重要。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物应用。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

高风险级别生物产品--人源产品

此项目有



历史批次信息供参考:

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实验方案

A step-by-step protocol for released N-linked glycan analysis of the monoclonal antibody adalimumab, based on UHPLC-FLR-MS and procainamide labeling.

商品

PNGase Fast denaturing buffer and enzyme provide results similar to a conventional 20-hour protocol, reducing workflow time to about 1 hour.

Glycan profiling of monoclonal antibodies using Ascentis® Express ZIC®-cHILIC columns enables high-resolution IgG glycan separation with improved efficiency and speed.

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Katinka Döhner et al.
Molecular biology of the cell, 13(8), 2795-2809 (2002-08-16)
After fusion of the viral envelope with the plasma membrane, herpes simplex virus type 1 (HSV1) capsids are transported along microtubules (MTs) from the cell periphery to the nucleus. The motor ATPase cytoplasmic dynein and its multisubunit cofactor dynactin mediate
Nils A Brechmann et al.
Biotechnology progress, 35(3), e2775-e2775 (2019-01-11)
High capacity magnetic protein A agarose beads, LOABeads PrtA, were used in the development of a new process for affinity purification of monoclonal antibodies (mAbs) from non-clarified CHO cell broth using a pilot-scale magnetic separator. The LOABeads had a maximum
Youhei Egami et al.
Journal of cell science, 130(24), 4168-4179 (2017-11-09)
Phagosome formation is a complicated process that requires spatiotemporally regulated actin reorganization. We found that RhoC GTPase is a critical regulator of FcγR-mediated phagocytosis in macrophages. Our live-cell imaging revealed that RhoC, but not RhoA, is recruited to phagocytic cups



全球贸易项目编号

货号GTIN
I4506-500MG04061833856864
I4506-100MG04061833856840
I4506-10MG04061833856857
I4506-50MG04061833856871