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Merck
CN

H4663

Sigma-Aldrich

HMBA

≥98% (HPLC), solid

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别名:
10-[(3-Hydroxy-4-methoxybenzylidene)]-9(10H)-anthracenone
经验公式(希尔记法):
C22H16O3
分子量:
328.36
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

solid

溶解性

DMSO: soluble 34 mg/mL

储存温度

−20°C

SMILES字符串

COc1ccc(cc1O)\C=C2\c3ccccc3C(=O)c4ccccc24

InChI

1S/C22H16O3/c1-25-21-11-10-14(13-20(21)23)12-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-13,23H,1H3

InChI key

MQLACMBJVPINKE-UHFFFAOYSA-N

生化/生理作用

HMBA is an Inhibitor of microtubule polymerization; apoptosis inducer.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Nucleophosmin (NPM, also known as B23), mainly localized in the nucleolus, has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. NPM was identified while screening the differential nuclear matrix proteins

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