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H4663

Sigma-Aldrich

HMBA

≥98% (HPLC), solid

Synonym(s):

10-[(3-Hydroxy-4-methoxybenzylidene)]-9(10H)-anthracenone

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About This Item

Empirical Formula (Hill Notation):
C22H16O3
CAS Number:
564468-51-5
Molecular Weight:
328.36
MDL number:
MFCD06411568
UNSPSC Code:
12352200
PubChem Substance ID:
24724500
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 34 mg/mL

storage temp.

−20°C

SMILES string

COc1ccc(cc1O)\C=C2\c3ccccc3C(=O)c4ccccc24

InChI

1S/C22H16O3/c1-25-21-11-10-14(13-20(21)23)12-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-13,23H,1H3

InChI key

MQLACMBJVPINKE-UHFFFAOYSA-N

Biochem/physiol Actions

HMBA is an Inhibitor of microtubule polymerization; apoptosis inducer.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
054K4614

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Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP.
Olson, et al.
Molecular Cell, 82, 1708-1723 (2023)
Erwan Dupuis et al.
Talanta, 219, 121345-121345 (2020-09-06)
Capillary electrophoresis (CE) was hyphenated to multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) to determine the model age of a highly enriched uranium (HEU) sample using the 234U/230Th radiochronometer. The use of hydroxymethylbutyric acid (HMBA) as the CE electrolyte was
Seung Han Son et al.
International journal of molecular sciences, 23(12) (2022-06-25)
CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies including cancer. Despite its importance, many fundamental regulatory
Dong-Hui Xu et al.
International journal of oncology, 45(1), 264-272 (2014-05-03)
Nucleophosmin (NPM, also known as B23), mainly localized in the nucleolus, has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. NPM was identified while screening the differential nuclear matrix proteins
Olga S Safronova et al.
Nucleic acids research, 42(14), 8954-8969 (2014-07-25)
Hypoxia is associated with a variety of physiological and pathological conditions and elicits specific transcriptional responses. The elongation competence of RNA Polymerase II is regulated by the positive transcription elongation factor b (P-TEFb)-dependent phosphorylation of Ser2 residues on its C-terminal
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