All Photos(2)
Synonym(s):
N,N′-Diacetyl-1,6-hexanediamine, HMBA
Linear Formula:
CH3CONH(CH2)6NHCOCH3
CAS Number:
Molecular Weight:
200.28
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
98%
mp
128-129 °C (lit.)
solubility
water: soluble 5%, clear, colorless
SMILES string
CC(=O)NCCCCCCNC(C)=O
InChI
1S/C10H20N2O2/c1-9(13)11-7-5-3-4-6-8-12-10(2)14/h3-8H2,1-2H3,(H,11,13)(H,12,14)
InChI key
BNQSTAOJRULKNX-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
Application
N,N′-Hexamethylene bis(acetamide) was used as an inducing agent in obtaining mononuclear cells from the peripheral blood (PB) sample by Ficoll-Hypaque gradient separation.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Kara G Lassen et al.
PloS one, 7(1), e30176-e30176 (2012-02-01)
Latently infected cells form the major obstacle to HIV eradication. Studies of HIV latency have been generally hindered by the lack of a robust and rapidly deployable cell model that involves primary human CD4 T lymphocytes. Latently infected cell lines
Shailesh K Choudhary et al.
The Journal of infectious diseases, 197(8), 1162-1170 (2008-04-19)
Novel therapeutic approaches are needed to attack persistent proviral human immunodeficiency type 1 (HIV-1) infection. Hexamethylbisacetamide (HMBA), a hybrid bipolar compound, induces expression of the HIV-1 promoter in the long terminal repeat (LTR) region in a Tat-independent manner but mimics
Samuel T Workenhe et al.
Communications biology, 3(1), 645-645 (2020-11-06)
Cancer immunotherapies using monoclonal antibodies to block inhibitory checkpoints are showing durable remissions in many types of cancer patients, although the majority of breast cancer patients acquire little benefit. Human melanoma and lung cancer patient studies suggest that immune checkpoint
Wali Hafezi et al.
PLoS pathogens, 8(5), e1002679-e1002679 (2012-05-17)
Following productive, lytic infection in epithelia, herpes simplex virus type 1 (HSV-1) establishes a lifelong latent infection in sensory neurons that is interrupted by episodes of reactivation. In order to better understand what triggers this lytic/latent decision in neurons, we
Richard L Thompson et al.
PLoS pathogens, 5(3), e1000352-e1000352 (2009-03-28)
The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet interactions between host and viral functions that govern this process remain unclear. The cascade of HSV gene
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service