1.41544
Parteck® 聚乙烯醇
EMPROVE® ESSENTIAL, Ph. Eur.
别名:
Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
agency
Ph. Eur.
Quality Segment
product line
EMPROVE® ESSENTIAL
form
powder
application(s)
pharmaceutical
solid formulation
solubility enhancement
storage temp.
15-25°C
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI key
IMROMDMJAWUWLK-UHFFFAOYSA-N
General description
With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interactions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologically relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.
Application
Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.
Features and Benefits
- Superior supersaturation performance via precipitation inhibition
- High thermostability up to 250°C, extending the potential application range
- Stable high drug loads and suitability with a broad range of APIs
- Flexible release kinetics
- Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
- Optimized powder properties for excellent performance in the HME process
- Suitable polymer properties for HME, spray drying and 3D printing processes
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
使用 Emprove® 计划保持符合 GMP 要求
使用Emprove® Dossiers可加快资格认证、保持合规性并节省时间。
下载 Dossiers
注意：您将进入 EmproveSuite.com。您的用户名和密码与 SigmaAldrich.com 是分开的，可能不同。
免费注册，几分钟内即可访问 Emprove® Dossiers。 升级您的订阅计划，解锁 Emprove® Suite 中的高级定制内容。
没有找到您要找的内容？访问 Emprove® 计划帮助页面。