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Merck
CN

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

别名:
CAE2, ECA2, GEFSP3
物种:
Human GABRG2 (2566), Mouse Gabrg2 (14406), Rat Gabrg2 (29709), Horse GABRG2 (100059571), sheep GABRG2 (101118526), Zebrafish gabrg2 (553402), chicken GABRG2 (396289), dog GABRG2 (489141), domestic cat GABRG2 (100286791), cow GABRG2 (282240) ...展开
UniProtKB ID:
P18507, F5HB82, Q6GRL6, Q6PCC3, Q9UDB3, Q9UN15
基因ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

货号
说明
物种
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
PHR1663
丙泊酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
1572503
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
P-076
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Y0000016
普鲁泊福, European Pharmacopoeia (EP) Reference Standard,
物种
human
A0357000
阿普唑仑, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
1273808
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
G7795
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
D126608
丙泊酚, 97%,
物种
human
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat
A6981
阿坎酸钙, ≥98% (HPLC), powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
AB5559
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
物种反应性
rat
应用
immunoprecipitation (IP)
western blot
MABN263
Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8, clone 10F10-C1-B8, from mouse,
物种反应性
rat
应用
immunocytochemistry
western blot
AB10532
Anti-GABA(A) receptor subunit gamma-2 Antibody, serum, from rabbit,
物种反应性
human, rat
应用
western blot
MABN875
抗-GABAA抗体γ2亚基，克隆KC4-8A7, clone KC4-8A7, from mouse,
物种反应性
bovine, human, mouse, rat
应用
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2501406
Anti-GABRG2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human, mouse, rat
应用
ELISA
western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
G7795
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse

esiRNA

货号
说明
物种
EHU083141
MISSION® esiRNA, targeting human GABRG2,
物种
human