SAB4504393
Anti-phospho-eNOS (pSer1176) antibody produced in rabbit
affinity isolated antibody
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All Photos(13)
Synonym(s):
Anti-ECNOS, Anti-eNOS
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 133 kDa
species reactivity
rat, human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer1176)
Gene Information
human ... NOS3(4846)
General description
Nitric oxide synthase 3 (NOS3), also known as endothelial nitric oxide synthase (eNOS), is encoded by the gene mapped to human chromosome 7q35-36. The gene consists of 26 exons.
Immunogen
The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser1176.
Immunogen Range: 1144-1193
Immunogen Range: 1144-1193
Biochem/physiol Actions
Nitric oxide synthase 3 (NOS3) has been studied as a modulator of vascular function and is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Marwa Ben Ali et al.
Genetic testing and molecular biomarkers, 19(4), 203-208 (2015-03-10)
Nitric oxide (NO), produced by the enzyme endothelial nitric oxide synthase (eNOS), has critical roles in the regulation of vascular homeostasis and prevention of atherogenesis by inhibiting leukocytes, platelet activation, and smooth muscle cell proliferation. There is strong experimental and
Bing Yi et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(10), 2153-2160 (2015-08-22)
Endothelial nitric oxide synthase (eNOS) is an important regulator of vascular function and its expression is regulated at post-transcriptional levels through a yet unknown mechanism. The purpose of this study is to elucidate the post-transcriptional factors regulating eNOS expression and
Lorraine Eley et al.
Disease models & mechanisms, 17(1) (2023-12-19)
eNOS (NOS3) is the enzyme that generates nitric oxide, a signalling molecule and regulator of vascular tone. Loss of eNOS function is associated with increased susceptibility to atherosclerosis, hypertension, thrombosis and stroke. Aortopathy and cardiac hypertrophy have also been found
Zhaohui Fang et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(6), 683-691 (2020-06-20)
Medicinal plants act as an alternative source of anti-diabetic agents. Recently, Danzhi Jiangtang capsule (DJC) has been clinically used for treatment of diabetes, but the effect of DJC on diabetic macroangiopathy remained unclear. The present study investigates the therapeutic role
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