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SAB4300103

Sigma-Aldrich

Anti-phospho-LIMK1 (pThr508) antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Anti-LIM domain kinase 1 antibody produced in rabbit, Anti-LIMK antibody produced in rabbit
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~72 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(R-Y-TP-V-V)

NCBI accession no.

NP_002305.1

UniProt accession no.

P53667

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr508)

Gene Information

human ... LIMK1(3984)

Immunogen

Peptide sequence around phosphorylation site of threonine 508 (R-Y-T(p)-V-V), according to the protein LIMK1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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