SAB2501926
Anti-IDO1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
Sign Into View Organizational & Contract Pricing
All Photos(1)
CD107B, HGNC:6059, IDO, INDO, indoleamine-pyrrole 2,3 dioxygenase
Recommended Products
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: suitable
indirect ELISA: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IDO1(3620)
General description
Indoleamine 2,3 dioxygenase (IDO) 1 is one of the four tryptophan catabolic enzymes in mammals. It codes for a full-length protein, made up of 403 amino acids and has a molecular weight of 45,332 Daltons. It is present in the cytosol. IDO1 is located on human chromosome 8p11.
Immunogen
Peptide with sequence CVLANWKKKDPNK, from the internal region of the protein sequence according to NP_002155.1
Biochem/physiol Actions
Indoleamine 2,3 dioxygenase (IDO) 1 plays an important role in the metabolism of tryptophan and in immune regulation. Removal of IDO1 results in attenuated contact hypersensitivity (CHS) responses.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
含少量动物源组分生物产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
IDO1 (indoleamine 2, 3-dioxygenase 1)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2010)
Indoleamine-2, 3-dioxygenase (IDO) 2 polymorphisms are not associated with multiple sclerosis in Italians
Journal of the Neurological Sciences, 377, 31-34 (2017)
International immunology, 26(7), 357-367 (2014-01-10)
IDO2 is implicated in tryptophan catabolism and immunity but its physiological functions are not well established. Here we report the characterization of mice genetically deficient in IDO2, which develop normally but exhibit defects in IDO-mediated T-cell regulation and inflammatory responses.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service