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Key Documents

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PHG0005

SAFC

BIS-TRIS propane

Synonym(s):

1,3-Bis[tris(hydroxymethyl)methylamino]propane

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About This Item

Linear Formula:
CH2[CH2NHC(CH2OH)3]2
CAS Number:
64431-96-5
Molecular Weight:
282.33
Beilstein:
1786109
EC Number:
264-899-3
MDL number:
MFCD00004689
UNSPSC Code:
12161705
NACRES:
NA.21
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

400

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

useful pH range

6.3-9.5

pKa (25 °C)

(1) 6.8, (2) 9.0

mp

164-165 °C (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

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Show Differences

1 of 4

This Item
PHR148158958V319902
乙酸乙酯 Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

EX0240

乙酸乙酯

乙酸乙酯 Pharmaceutical Secondary Standard; Certified Reference Material

PHR1481

乙酸乙酯

乙酸乙酯 analytical standard

58958

乙酸乙酯

乙酸乙酯 ACS reagent

V319902

乙酸乙酯

assay

≥99.5% (GC)

assay

-

assay

≥99.9% (GC)

assay

-

application(s)

environmental
food and beverages
industrial qc
pharmaceutical
sample preparation

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

application(s)

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

grade

ACS reagent, for extraction, for analytical purposes, reagent grade

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

grade

ACS reagent

form

liquid

form

-

form

-

form

-

vapor density

3 (20 °C, vs air)

vapor density

3 (20 °C, vs air)

vapor density

3 (20 °C, vs air)

vapor density

3 (20 °C, vs air)

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

Bis Tris Propane is a unique biological buffer also referred to as a “Universal” buffer, which means the buffer capacity covers a wide range. Bis Tris Propane has two pKas of 6.3 and 9.5, which expands the buffering range from 5.0-10.5-making this a versatile buffer for biological systems. Bis Tris Propane is considered to be non-toxic to culture cell lines and provides high-solution clarity.

A review of DNA polymerase techniques lists bis tris propane as a suitable buffer for PCR methods as a universal buffer pH gradient is employed.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

replaced by

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000352922
    0000350928
    0000345538
    0000345533
    0000345534

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