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N8285

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide

pkg of 10 mg (per vial)

Synonym(s):

β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, Nadide

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15 VIALS
CN¥1,993.65

CN¥1,993.65

List PriceCN¥2,848.06Save 30%

Available to ship onApril 24, 2025Details

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15 VIALS
CN¥1,993.65

About This Item

Empirical Formula (Hill Notation):
C21H27N7O14P2
CAS Number:
53-84-9
Molecular Weight:
663.43
Beilstein:
3584133
EC Number:
200-184-4
MDL number:
MFCD00036253
UNSPSC Code:
41106305
eCl@ss:
39200202
PubChem Substance ID:
57654466
NACRES:
NA.51

CN¥1,993.65

List PriceCN¥2,848.06Save 30%

Available to ship onApril 24, 2025Details

Request a Bulk Order

biological source

yeast

Quality Level

200

form

powder

packaging

pkg of 10 mg (per vial)

solubility

H2O: soluble-50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Gene Information

human ... ESR1(2099) , ESR2(2100)

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Show Differences

1 of 4

This Item
N8410N8535N1636
β-Nicotinamide adenine dinucleotide pkg of 10 mg (per vial)

N8285

β-Nicotinamide adenine dinucleotide

β-Nicotinamide adenine dinucleotide pkg of 20 mg (per vial)

N8410

β-Nicotinamide adenine dinucleotide

β-Nicotinamide adenine dinucleotide pkg of 50 mg (per vial)

N8535

β-Nicotinamide adenine dinucleotide

β-Nicotinamide adenine dinucleotide hydrate purified by column chromatography, ≥99%

N1636

β-Nicotinamide adenine dinucleotide hydrate

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

powder

form

powder

form

crystalline powder

packaging

pkg of 10 mg (per vial)

packaging

pkg of 20 mg (per vial)

packaging

pkg of 50 mg (per vial)

packaging

-

Gene Information

human ... ESR1(2099), ESR2(2100)

Gene Information

-

Gene Information

human ... ESR1(2099), ESR2(2100)

Gene Information

-

Application

β-Nicotinamide adenine dinucleotide (β-NAD) has been used for the preparation of deacetylated tubulin.[1] It has also been used for UDP-glucose-6-hydrogenase (UGDH) enzyme activity assay of orital fibroblast cell lysates.[2]

Biochem/physiol Actions

β-Nicotinamide adenine dinucleotide (β-NAD) is a neuromodulator and an inhibitory neurotransmitter. It is an agonist for purinergic (P2Y1) receptors.[3]
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
Electron acceptor

Other Notes

Packaged based on NAD content as determined by UV-Vis.
This is the common form of NAD.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000417252
    0000417252
    0000377056
    0000377056
    0000268787

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    Luminal localization of $\alpha$-tubulin K40 acetylation by cryo-EM analysis of fab-labeled microtubules
    Soppina V, et al.
    PLoS ONE, 7(10), e48204-e48204 (2012)
    Violeta N Mutafova-Yambolieva et al.
    Proceedings of the National Academy of Sciences of the United States of America, 104(41), 16359-16364 (2007-10-05)
    Peripheral inhibitory nerves are physiological regulators of the contractile behavior of visceral smooth muscles. One of the transmitters responsible for inhibitory neurotransmission has been reputed to be a purine, possibly ATP. However, the exact identity of this substance has never
    Xiongjun Wang et al.
    Molecular cell, 76(1), 148-162 (2019-08-27)
    The rapid proliferation of cancer cells and dysregulated vasculature within the tumor leads to limited nutrient accessibility. Cancer cells often rewire their metabolic pathways for adaption to nutrient stress, and the underlying mechanism remains largely unknown. Glutamate dehydrogenase 1 (GDH1)
    Richard P Ebstein et al.
    FEBS letters, 585(11), 1529-1536 (2011-05-12)
    Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
    Ana P Gomes et al.
    Cell, 155(7), 1624-1638 (2013-12-24)
    Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
    View All Related Papers

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