L4879
Lumiflavine
powder
Synonym(s):
7,8,10-Trimethylbenzo[g]pteridine-2,4(3H,10H)-dione, 7,8,10-Trimethylisoalloxazine
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About This Item
Empirical Formula (Hill Notation):
C13H12N4O2
CAS Number:
Molecular Weight:
256.26
Beilstein:
269756
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
form
powder
storage temp.
−20°C
SMILES string
CN1c2cc(C)c(C)cc2N=C3C(=O)NC(=O)N=C13
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Biochem/physiol Actions
Lumiflavine (Lumiflavin) is produced by the photolysis of vitamin B2 (Riboflavin). Lumiflavine, a riboflavin uptake inhibitor, is used to study riboflavin uptake in intestinal epithelial (Caco-2) and other epithelial cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Muta. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Minako Kondo et al.
The journal of physical chemistry. B, 110(41), 20107-20110 (2006-10-13)
Ultrafast time-resolved infrared (TRIR) spectra of flavin adenine dinucleotide (FAD) and the anion of lumiflavin (Lf-) are described. Ground-state recovery and excited-state decay of FAD reveal a common dominant ultrafast relaxation and a minor slower component. The Lf- transient lacks
Yoong-Kee Choe et al.
Journal of computational chemistry, 28(4), 727-739 (2007-01-18)
Time-dependent density functional theory has been applied to investigate the electronic absorption spectrum of oxidized and reduced lumiflavin and its derivative, 8-NH(2)-lumiflavin. The calculations allow the authors to explain the origin of the difference in spectral features between oxidized and
Yasuyuki Yamada et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 11(8), 1007-1023 (2006-09-01)
DNA photolyases (EC 4.1.99.3) are enzymes that catalyze photoreversion of cis,syn-thymine photodimer (T[c,s]T), which is one of major photolesion products in DNA, by utilizing UV light. In this work, we have designed and synthesized Zn2+ -1,4,7,10-tetraazacyclododecane complexes bearing a lumiflavin
H M Said et al.
The American journal of physiology, 266(1 Pt 1), G15-G21 (1994-01-01)
The cellular and molecular regulation of intestinal absorption of the water-soluble vitamin riboflavine (RF) is poorly understood. The availability of a suitable in vitro cultured system that possesses the transport characteristics of the native intestinal absorptive cells would provide a
Maxime T A Alexandre et al.
Biophysical journal, 97(1), 227-237 (2009-07-08)
Phototropins, major blue-light receptors in plants, are sensitive to blue light through a pair of flavin mononucleotide (FMN)-binding light oxygen and voltage (LOV) domains, LOV1 and LOV2. LOV2 undergoes a photocycle involving light-driven covalent adduct formation between a conserved cysteine
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