103217
Lumichrome
Synonym(s):
7,8-Dimethylalloxazine
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About This Item
Empirical Formula (Hill Notation):
C12H10N4O2
CAS Number:
Molecular Weight:
242.23
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
form
powder, crystals or chunks
Quality Level
technique(s)
titration: suitable
mp
>300 °C (lit.)
λmax
350 nm
392 nm (2nd)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cc1cc2nc3NC(=O)NC(=O)c3nc2cc1C
InChI
1S/C12H10N4O2/c1-5-3-7-8(4-6(5)2)14-10-9(13-7)11(17)16-12(18)15-10/h3-4H,1-2H3,(H2,14,15,16,17,18)
InChI key
ZJTJUVIJVLLGSP-UHFFFAOYSA-N
Related Categories
General description
Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. It is a flourescent photoproduct of riboflavin degradation. It is known to be an effective photosensitizer and a fluorescent dye.
Application
Lumichrome is suitable as a fluorescence probe, metal ion sensor, and may be used for the inactivation of biological contaminants. Its applications are also seen in memory and semiconductor devices.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Chuan Liu et al.
Journal of cellular physiology, 233(11), 8971-8983 (2018-06-16)
The dynamic balance between bone resorption and bone formation is crucial to maintain bone mass. Osteoclasts are key cells that perform bone resorption while osteoblasts and osteocytes function in bone formation. Osteoporosis, a bone metabolism disease characterized by bone loss
Partha Bairi et al.
The journal of physical chemistry. B, 114(35), 11454-11461 (2010-08-19)
Lumichrome (L) and melamine (M) produce thermoreversible hydrogels in LM31 and LM11 compositions, but LM13 composition does not produce hydrogel (the numbers indicate the respective molar ratio of the components). The formation of thermoreversible gels is confirmed from morphology, DSC
Sathish Rajamani et al.
Molecular plant-microbe interactions : MPMI, 21(9), 1184-1192 (2008-08-15)
Many bacteria use quorum sensing (QS) as an intercellular signaling mechanism to regulate gene expression in local populations. Plant and algal hosts, in turn, secrete compounds that mimic bacterial QS signals, allowing these hosts to manipulate QS-regulated gene expression in
Maria Marchena et al.
The journal of physical chemistry. B, 115(10), 2424-2435 (2011-02-22)
We report on photophysical studies of lumichrome (Lc) in water at different pHs, and interacting with the human serum albumin (HSA) protein and β-cyclodextrin (β-CD) in neutral aqueous solutions. We used steady-state and picosecond time-resolved emission spectroscopy to investigate the
Tamutenda Chidawanyika et al.
mBio, 11(4) (2020-08-14)
Extracellular hydrogen peroxide can induce oxidative stress, which can cause cell death if unresolved. However, the cellular mediators of H2O2-induced cell death are unknown. We determined that H2O2-induced cytotoxicity is an iron-dependent process in HAP1 cells and conducted a CRISPR/Cas9-based
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