HLP103
Normal Human Characterized Plateable Hepatocytes Small Volume Plateable (96 well)
Single-Donor Cryopreserved Primary Human Hepatocytes, suitable for cell culture in small volume (96 well plate), high viability and confluency for >5 days, characterized for mRNA induction and metabolic assay profiling.
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Homogenous population isolated from whole human livers
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biological source
human liver
form
frozen liquid
packaging
pkg of 1 vial (contains ≥4 million cells)
technique(s)
cell culture | mammalian: suitable
color
cloudy
storage temp.
-140 to -196°C
General description
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. Primary Human Hepatocytes are cells directly harvested from whole human livers and are used by researchers in vitro to model the physiology and function of Hepatocytes. As one of the major cell types of the liver, Hepatocytes function in protein, carbohydrate, and lipid metabolism and help to maintain liver homeostasis.
Application
Cryopreserved primary human plateable hepatocytes offer a versatile in vitro culture system, providing essential resources for investigating enzyme induction, toxicity, drug screening, transporter efflux activity, potential drug-drug interactions, and disease modeling.
Features and Benefits
Our plateable Hepatocytes collection consists of a homogeneous cell population, with each donor providing documented consent for research use of non-transplantable organs or tissues. These cells undergo extensive characterization, including mRNA induction data, enzyme profiling data, and morphological assessments, with a guaranteed post-thaw viability of ≥70%. In addition, all cells have been tested for the absence of HIV, HBV, HCV, Syphillis and microbial contaminants (fungi, bacteria, and mycoplasma).
Warning
Each donor is tested and found non-reactive to viral DNA from HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C. However, no known test can offer complete assurance that the viruses that cause HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C are not present. Proper precautions and biological containment should be taken when handling cells of human origin, due to their potential biohazardous nature. All human based products should be handled at a BSL-2 (Biosafety Level 2) or higher.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Hepatocytes: A key role in liver inflammation
Frontiers in Immunology, 13, 1083780-1083780 (2023)
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