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C8503

Sigma-Aldrich

Cholesterol

from sheep wool, ≥92.5% (GC), powder

Synonym(s):

3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

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25 G
¥667.16
100 G
¥1,273.19
500 G
¥5,975.42
1 KG
¥7,869.85
5 KG
¥28,095.01

¥667.16

Available to ship on2025年4月25日Details

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25 G
¥667.16
100 G
¥1,273.19
500 G
¥5,975.42
1 KG
¥7,869.85
5 KG
¥28,095.01

About This Item

Empirical Formula (Hill Notation):
C27H46O
CAS Number:
57-88-5
Molecular Weight:
386.65
Beilstein:
1915888
EC Number:
200-353-2
MDL number:
MFCD00003646
UNSPSC Code:
41141804
eCl@ss:
39023139
PubChem Substance ID:
24893064
NACRES:
NA.77

¥667.16

Available to ship on2025年4月25日Details

Request a Bulk Order

biological source

sheep wool

Quality Level

200

Assay

≥92.5% (GC)

form

powder

bp

360 °C (lit.)

mp

147-149 °C (lit.)

solubility

water: soluble 0.00003 g/L at 20 °C

density

1.067 g/mL at 25 °C (lit.)

shipped in

ambient

storage temp.

room temp

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1 of 4

This Item
C304526732PHR1533
胆固醇 from sheep wool, ≥92.5% (GC), powder

C8503

胆固醇

胆固醇 powder, BioReagent, suitable for cell culture, ≥99%

C3045

胆固醇

胆固醇 from lanolin, ≥99.0% (GC)

26732

胆固醇

胆固醇 Pharmaceutical Secondary Standard; Certified Reference Material

PHR1533

胆固醇

assay

≥92.5% (GC)

assay

≥99%

assay

≥99.0% (GC)

assay

-

biological source

sheep wool

biological source

ovine wool

biological source

lanolin

biological source

-

solubility

water: soluble 0.00003 g/L at 20 °C

solubility

H2O: 0.002 mg/mL, Tween: soluble, ethanol: soluble, serum: soluble

solubility

chloroform: 0.1 g/mL, clear, colorless

solubility

water: soluble 0.00003 g/L at 20 °C

storage temp.

room temp

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

shipped in

ambient

shipped in

ambient

shipped in

-

shipped in

-

form

powder

form

powder

form

powder

form

powder

Application

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses.[1] It was incorporated in animal feed to study the effect of cholesterol-rich diet.[2][3]

Biochem/physiol Actions

Cholesterol is a lipid makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane.[4] The major sites of cholesterol synthesis are small intestine and liver.[5]
Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000438690
    0000438690
    0000443398
    0000443397
    0000443395

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    Effects of 2 or 5 consecutive exercise days on adipocyte area and lipid parameters in Wistar rats
    Guerra RL et al
    Lipids in Health and Disease, 6, doi: 10-doi: 10 (2007)
    Effects of probiotic bacteria, isoflavones and simvastatin on lipid profile and atherosclerosis in cholesterol-fed rabbits: a randomized double-blind study
    Cavallini DC et al
    Lipids in Health and Disease, 8, doi: 10-doi: 10 (2009)
    Anja Helgeby et al.
    Journal of immunology (Baltimore, Md. : 1950), 176(6), 3697-3706 (2006-03-07)
    The cholera toxin A1 (CTA1)-DD/QuilA-containing, immune-stimulating complex (ISCOM) vector is a rationally designed mucosal adjuvant that greatly potentiates humoral and cellular immune responses. It was developed to incorporate the distinctive properties of either adjuvant alone in a combination that exerted
    John M Dietschy et al.
    Journal of lipid research, 45(8), 1375-1397 (2004-07-16)
    Unesterified cholesterol is an essential structural component of the plasma membrane of every cell. During evolution, this membrane came to play an additional, highly specialized role in the central nervous system (CNS) as the major architectural component of compact myelin.
    R R Grummer et al.
    Journal of animal science, 66(12), 3160-3173 (1988-12-01)
    Cholesterol utilized for steroid synthesis by ovarian tissue may be derived from de novo synthesis or cellular uptake of lipoprotein cholesterol. The majority of blood cholesterol is transported by either low (LDL) or high (HDL) density lipoproteins, depending on the
    View All Related Papers

    Articles

    Cholesterol Biosynthesis

    Cholesterol biosynthesis starts in the hepatic endoplasmic reticulum with acetyl-CoA, yielding 3-hydroxy-3-methylglutaryl-CoA via HMG-CoA synthase.

    Protocols

    Enzymatic Assay of Cholesterol Oxidase

    Enzymatic activity assay for cholesterol oxidase, excluding specific product numbers, providing guidelines for accurate cholesterol oxidase assays.

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