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Merck
CN

C7263

Sigma-Aldrich

Calcium phosphate dibasic

98.0-105.0%

Synonym(s):

Calcium hydrogen phosphate

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1 G
CN¥2,212.69
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CN¥1,535.06
10 G
CN¥6,553.54

CN¥2,212.69


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1 G
CN¥2,212.69
5 G
CN¥1,535.06
10 G
CN¥6,553.54

About This Item

Linear Formula:
CaHPO4
CAS Number:
Molecular Weight:
136.06
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

CN¥2,212.69


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Quality Level

Assay

98.0-105.0%

form

powder

SMILES string

[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

InChI key

FUFJGUQYACFECW-UHFFFAOYSA-L

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Show Differences

1 of 4

This Item
323667430471764817
transition temp

Tm 220-230 °C

transition temp

Tg 106 °C

transition temp

Tg 45-50 °C

transition temp

Tm 230-235 °C

form

solid

form

-

form

amorphous

form

semisolid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

density

1.53 g/mL at 25 °C (lit.)

density

-

density

-

density

-

degradation timeframe

6-12 months

degradation timeframe

-

degradation timeframe

<6 months

degradation timeframe

2-3 weeks

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

inherent viscosity

-

inherent viscosity

-

inherent viscosity

-

Application

Calcium phosphate dibasic has been used:
  • to prepare high temperature stoichiometric sintered hydroxyapatite (sin-HA)[1]
  • as a component of calcium phosphate cement (CPC) to prepare bioartificial pancreas (BAP)[2]
  • to produce calcium pyrophosphate (Ca2P2O7) for the preparation of α-tricalcium phosphates (α-TCP)[3]

Biochem/physiol Actions

Calcium phosphate dibasic is an anhydrate used to dilute tablets and capsules. It is widely used as an excipient for its compressibility, amenability, and brittle fracture propensity.[4]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Kai-Chiang Yang et al.
Transplantation, 90(6), 604-611 (2010-01-06)
Fibrous tissue outgrowth and hypoxia are the major restrictions for the application of bioartificial pancreas (BAP). Accordingly, the intramedullary cavity is proposed as an implant site, and a BAP constructed of calcium phosphate cement chamber was implanted. Mouse insulinoma cells
Aditya M Kaushal et al.
Journal of pharmaceutical sciences, 100(4), 1456-1466 (2011-04-01)
Dibasic calcium phosphate occurs as an anhydrate (DCPA; CaHPO₄) and as a dihydrate (DCPD; CaHPO₄•2H₂O). Our objective was to investigate the unusual behavior of these phases. Dibasic calcium phosphate dihydrate was dehydrated in a (i) differential scanning calorimeter (DSC) in
Anna Diez-Escudero et al.
Tissue engineering. Part C, Methods, 23(2), 118-124 (2017-01-14)
This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal microstructural changes at a level of
C L Camiré et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 79(1), 159-165 (2006-04-15)
Alpha phase tricalcium phosphates (alpha-TCP) were produced using a solid-state reaction method and milled for various periods of time. The resulting four materials were alpha-TCPs, ranging in crystalline content. Powders were exposed to X-ray diffraction for material identification as well
Nariman Mansoori Boroujeni et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4323-4330 (2013-08-06)
In this study, we present results of our research on biodegradable monetite (DCPA, CaHPO4) cement with surface-modified multi-walled carbon nanotubes (mMWCNTs) as potential bone defect repair material. The cement pastes showed desirable handling properties and possessed a suitable setting time

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