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289396

Sigma-Aldrich

Hydroxyapatite

reagent grade, powder, synthetic

Synonym(s):

Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate

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CN¥6,780.43

CN¥6,780.43

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About This Item

Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
12167-74-7
Molecular Weight:
502.31
EC Number:
235-330-6
MDL number:
MFCD00010904
UNSPSC Code:
12352302
PubChem Substance ID:
57648308
NACRES:
NA.23
grade:
reagent grade
form:
powder
solid
solubility:
H2O: insoluble(lit.)

CN¥6,780.43

Available to ship onApril 27, 2025Details

Request a Bulk Order

grade

reagent grade

Quality Level

100

form

powder
solid

mp

1100 °C (lit.)

solubility

H2O: insoluble(lit.)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Show Differences

1 of 4

This Item
677418702153693863
Hydroxyapatite reagent grade, powder, synthetic

289396

Hydroxyapatite

Hydroxyapatite nanopowder, <200 nm particle size (BET), ≥97%, synthetic

677418

Hydroxyapatite

Hydroxyapatite nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

702153

Hydroxyapatite

Hydroxyapatite nanopowder, <200 nm particle size (BET), contains 5 wt. % silica as dopant, synthetic

693863

Hydroxyapatite

form

powder, solid

form

nanopowder, solid

form

dispersion, nanoparticles

form

nanopowder, solid

solubility

H2O: insoluble(lit.)

solubility

-

solubility

-

solubility

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

reagent grade

grade

-

grade

-

grade

-

mp

1100 °C (lit.)

mp

1100 °C (lit.)

mp

-

mp

1100 °C (lit.)

General description

Hydroxyapatite is a key inorganic phosphate that has chemical and structural resemblance to bone. HAp is a popular biomaterial which finds use as a bone or teeth replacement and repair, hard tissue repair. [1]

Application

Hydroxyapatite(HAp) was used to model intracranial calcification in a study.[2] HAp forms biocomposites with a number of polymers for various uses, such as:
  • for comparison purposes during the preparation of HAp based biocomposites with PVA and collagen.[3]
  • for preparation of poly(methyl methacrylate) (PMMA)/hydroxyapatite (HA) by powder liquid method to manufacture denture base composites.[4][5]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCV3990
    MKCT0405
    MKCS3320
    MKCQ5351
    MKCK2048

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    Biocomposites of nanohydroxyapatite with collagen and poly (vinyl alcohol).
    Degirmenbasi N, et al.
    Colloids and Surfaces. B, Biointerfaces, 48(1), 42-49 (2006)
    Hydroxyapatite and hydroxyapatite-based ceramics.
    Orlovskii VP, et al.
    Inorganic Materials, 38(10), 973-984 (2002)
    Effects of titanate coupling agent on the mechanical, thermal, and morphological properties of poly (methyl methacrylate)/hydroxyapatite denture base composites.
    Tham WL, et al.
    Journal of Composite Materials, 45(22), 2335-2345 (2011)
    Differentiation of low-attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system.
    Nute JL, et al.
    Investigative Radiology, 50(1), 9-9 (2015)
    Simulated body fluid and water absorption effects on poly (methyl methacrylate)/hydroxyapatite denture base composites.
    Tham WL, et al.
    Express Polymer Letters, 4(9), 517-528 (2010)
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