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457620

Sigma-Aldrich

Polyglycolide

inherent viscosity 1.4dL/g

Synonym(s):

PGA, Poly(glycolic acid)

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1 G
CN¥2,212.69
5 G
CN¥1,535.06
10 G
CN¥6,553.54

CN¥2,212.69

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1 G
CN¥2,212.69
5 G
CN¥1,535.06
10 G
CN¥6,553.54

About This Item

Linear Formula:
(C2H4O3)n
CAS Number:
26124-68-5
MDL number:
MFCD00148011
UNSPSC Code:
12162002
PubChem Substance ID:
24869373
NACRES:
NA.23

CN¥2,212.69

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

form

solid

degradation timeframe

6-12 months

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

transition temp

Tm 220-230 °C

solubility

hexafluoroisopropanol: soluble

density

1.53 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

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This Item
323667430471764817
Polyglycolide inherent viscosity 1.4dL/g

457620

Polyglycolide

Poly(acrylic acid)

323667

Poly(acrylic acid)

Poly(D,L-lactide-co-glycolide) ester terminated, Mw 50,000-75,000

430471

Poly(D,L-lactide-co-glycolide)

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide) average Mn (1100-1000-1100), lactide:glycolide 75:25

764817

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

transition temp

Tm 220-230 °C

transition temp

Tg 106 °C

transition temp

Tg 45-50 °C

transition temp

Tm 230-235 °C

form

solid

form

-

form

amorphous

form

semisolid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

density

1.53 g/mL at 25 °C (lit.)

density

-

density

-

density

-

degradation timeframe

6-12 months

degradation timeframe

-

degradation timeframe

<6 months

degradation timeframe

2-3 weeks

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

inherent viscosity

-

inherent viscosity

-

inherent viscosity

-

General description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration.[1] High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.[2]

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations.[3] Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite.[4] Modified porous PGA scaffolds has been fabricated.[1]
medical device

Physical properties

Biodegradable polymer

Preparation Note

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCV5213
    MKCN9577
    MKCC4011
    MKBQ7102V
    MKBJ2002V

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    Diopside modified porous polyglycolide scaffolds with improved properties
    Feng P, et al.
    Royal Society of Chemistry Advances, 5, 54822-54829 (2015)
    Effect of dsDNA wrapped single-walled carbon nanotubes on the thermal and mechanical properties of polycaprolactone and polyglycolide fiber blend composites
    Spearman SS
    Polymer, 56(15), 476-481 (2015)
    Fast Synthesis of High-Molecular-Weight Polyglycolide Using Diphenyl Bismuth Bromide as Catalyst
    Lu Y, et al.
    Macromolecular Chemistry and Physics, 216(4), 395-399 (2015)
    Preliminary report on the osteogenic potential of a biodegradable copolymer of polyactide (PLA) and polyglycolide (PGA)
    Hollinger JO
    Journal of Biomedical Materials Research Part A, 17(1) (1983)
    Andrew K Capulli et al.
    Biomaterials, 133, 229-241 (2017-04-27)
    Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. To overcome

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    Biodegradable Polyester Nanoparticle Formation

    AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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