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Merck
CN

46746

Polyglycolic acid

Synonym(s):

PGA, Poly(2-hydroxyacetic acid)

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About This Item

CAS Number:
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
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InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

description

inherent viscosity 1.2 dl/g

Application

medical device

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
M A Tiunin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Daniel E Levin et al.
Methods in molecular biology (Clifton, N.J.), 1001, 299-309 (2013-03-16)
Here, we describe the use of a mouse model as a living bioreactor for the generation of tissue-engineered small intestine. Small intestine is harvested from donor mice with subsequent isolation of organoid units (a cluster of mesenchymal and epithelial cells).
Richard G Payne et al.
Methods in molecular biology (Clifton, N.J.), 1001, 167-177 (2013-03-16)
This chapter describes the fabrication of a polyglycolic acid (PGA)-based scaffold used to tissue engineer a Neo-Urinary Conduit™.
Qingxing Xu et al.
Biomaterials, 34(15), 3902-3911 (2013-03-05)
The drug release and degradation behavior of two double-walled microsphere formulations consisting of a doxorubicin-loaded poly(d,l-lactic-co-glycolic acid) (PLGA) core (∼46 kDa) surrounded by a poly(d,l-lactic acid) (PDLLA) shell layer (∼55 and 116 kDa) were examined. It was postulated that different molecular weights

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