46746
Polyglycolic acid
Synonym(s):
PGA, Poly(2-hydroxyacetic acid)
description
inherent viscosity 1.2 dl/g
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Application
medical device
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M A Tiunin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
Daniel E Levin et al.
Methods in molecular biology (Clifton, N.J.), 1001, 299-309 (2013-03-16)
Here, we describe the use of a mouse model as a living bioreactor for the generation of tissue-engineered small intestine. Small intestine is harvested from donor mice with subsequent isolation of organoid units (a cluster of mesenchymal and epithelial cells).
Hongfen Wei et al.
PloS one, 8(3), e58133-e58133 (2013-03-08)
The distribution of targeted nanoparticles in tumor tissue is affected by a combination of various factors such as the physicochemical properties of the nanoparticles, tumor hemoperfusion and tumor vascular permeability. In this study, the impact of the biological effects of
Richard G Payne et al.
Methods in molecular biology (Clifton, N.J.), 1001, 167-177 (2013-03-16)
This chapter describes the fabrication of a polyglycolic acid (PGA)-based scaffold used to tissue engineer a Neo-Urinary Conduit™.
Articles
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
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